Cellosaurus cell line H314 (CVCL

Cellosaurus H314 (CVCL_2460)

Cross-references
Cell line name	H314
Accession	CVCL_2460
Resource Identification Initiative	To cite this cell line use: H314 (RRID:CVCL_2460)
Comments	Derived from site: In situ; Oral cavity, floor of mouth; UBERON=UBERON_0003679.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Cys176Phe (c.527G>T); ClinVar=VCV000376569; Zygosity=Homozygous (PubMed=7633286). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys373Glu (c.1117A>G); Zygosity=Homozygous (PubMed=7633286).
Disease	Floor of mouth squamous cell carcinoma (NCIt: C4041) Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	82Y
Category	Cancer cell line
Publications	PubMed=1692339; DOI=10.1002/path.1711600313 Stephen S. Prime, Sally V.R. Nixon, Isabel J. Crane, Andrea Stone, John B. Matthews, Norman J. Maitland, Lucy Remnant, Susan K. Powell, Stephen M. Game, Crispian Scully; The behaviour of human oral squamous cell carcinoma in cell culture. J. Pathol. 160:259-269(1990) PubMed=1744799; DOI=10.1002/path.1711650208 Serdar Mutlu, John B. Matthews, Marsh Midda, Crispian Scully, Stephen S. Prime; MHC antigen expression in human oral squamous carcinoma cell lines. J. Pathol. 165:129-136(1991) PubMed=7633286; DOI=10.1016/0964-1955(94)00030-8 William Andrew Yeudall, Ian C. Paterson, Vyomesh Patel, Stephen S. Prime; Presence of human papillomavirus sequences in tumour-derived human oral keratinocytes expressing mutant p53. Eur. J. Cancer B. Oral Oncol. 31:136-143(1995)
Cell line collections (Providers)	CancerTools; 153421 ECACC; 06092003 - Discontinued Ximbio; 153421
Cell line databases/resources	cancercelllines; CVCL_2460
Encyclopedic resources	Wikidata; Q54872065
Polymorphism and mutation databases	Cosmic; 716675 Cosmic; 916369 Cosmic; 928236
Entry history
Entry creation	04-Apr-2012
Last entry update	19-Dec-2024
Version number	18