Cellosaurus cell line H103 (CVCL

Cellosaurus H103 (CVCL_2457)

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Cell line name

H103

Accession

CVCL_2457

Resource Identification Initiative

To cite this cell line use: H103 (RRID:CVCL_2457)

Comments

Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Karyotypic information: Has lost chromosome Y.
Omics: Genomics; Whole exome sequencing.
Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.

Sequence variations

Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly244Cys (c.730G>T); ClinVar=VCV000376599; Zygosity=Homozygous (PubMed=7633286; DepMap=ACH-001346).

Disease

Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

32Y

Category

Cancer cell line

STR profile

Source(s): DepMap=ACH-001346; ECACC=06092001

Markers:

Amelogenin	X
CSF1PO	9,10
D3S1358	17
D5S818	10,11
D7S820	10
D8S1179	12,13
D13S317	12,13
D16S539	11,12
D18S51	15
D21S11	30
FGA	21,23
Penta D	9,11
Penta E	20
TH01	8,9
TPOX	8,9
vWA	14,16

Publications

PubMed=1692339; DOI=10.1002/path.1711600313
Stephen S. Prime, Sally V.R. Nixon, Isabel J. Crane, Andrea Stone, John B. Matthews, Norman J. Maitland, Lucy Remnant, Susan K. Powell, Stephen M. Game, Crispian Scully;
The behaviour of human oral squamous cell carcinoma in cell culture.
J. Pathol. 160:259-269(1990)

PubMed=1744799; DOI=10.1002/path.1711650208
Serdar Mutlu, John B. Matthews, Marsh Midda, Crispian Scully, Stephen S. Prime;
MHC antigen expression in human oral squamous carcinoma cell lines.
J. Pathol. 165:129-136(1991)

PubMed=7633286; DOI=10.1016/0964-1955(94)00030-8
William Andrew Yeudall, Ian C. Paterson, Vyomesh Patel, Stephen S. Prime;
Presence of human papillomavirus sequences in tumour-derived human oral keratinocytes expressing mutant p53.
Eur. J. Cancer B. Oral Oncol. 31:136-143(1995)

Cross-references

Cell line collections (Providers)

CancerTools; 153419
ECACC; 06092001 - Discontinued
Ximbio; 153419

Cell line databases/resources

Cell_Model_Passport; SIDM01568
DepMap; ACH-001346

Chemistry resources

ChEMBL-Cells; CHEMBL4483157
ChEMBL-Targets; CHEMBL4483241
PubChem_Cell_line; CVCL_2457

Encyclopedic resources

Wikidata; Q54871913

Polymorphism and mutation databases

Cosmic; 716673
Cosmic; 916367
Cosmic; 928234

Entry history

Entry creation

04-Apr-2012

Last entry update

10-Apr-2025

Version number