Cellosaurus HLF-a (CVCL_2255)
Cell line name | HLF-a | ||||||||||||||||||
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Synonyms | HLFa; HLFA | ||||||||||||||||||
Accession | CVCL_2255 | ||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: HLF-a (RRID:CVCL_2255) | ||||||||||||||||||
Comments | Problematic cell line: Misclassified. Originally thought to be a lung squamous cell carcinoma cell line but using a variety of omics methods was shown to be a a fibroblastic cell line (DOI=10.1101/166199; DepMap). Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). Population: African American. Omics: Deep exome analysis. Omics: SNP array analysis. Omics: Transcriptome analysis by microarray. Omics: Transcriptome analysis by RNAseq. Derived from sampling site: Lung. Cell type=Fibroblast. | ||||||||||||||||||
Genome ancestry | Source: PubMed=30894373
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Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||
Sex of cell | Female | ||||||||||||||||||
Age at sampling | 54Y | ||||||||||||||||||
Category | Undefined cell line type | ||||||||||||||||||
STR profile | Source(s): ATCC Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||
Publications | PubMed=7065527; DOI=10.1164/arrd.1982.125.2.222 PubMed=22460905; DOI=10.1038/nature11003 PubMed=24002593; DOI=10.1038/bjc.2013.452 DOI=10.1101/166199 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747 PubMed=31068700; DOI=10.1038/s41586-019-1186-3 | ||||||||||||||||||
Cross-references | |||||||||||||||||||
Cell line collections | ATCC; CCL-199
ECACC; 90112703 - Discontinued | ||||||||||||||||||
Cell line databases/resources | CLO; CLO_0003783
CLDB; cl1699 Cell_Model_Passport; SIDM01710 DepMap; ACH-000797 | ||||||||||||||||||
Biological sample resources | BioSample; SAMN03471463
BioSample; SAMN10988274 | ||||||||||||||||||
Chemistry resources | PharmacoDB; HLFa_550_2019 | ||||||||||||||||||
Encyclopedic resources | Wikidata; Q54889851 | ||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-2770
GEO; GSM206505 GEO; GSM274805 GEO; GSM274806 GEO; GSM887085 GEO; GSM888155 | ||||||||||||||||||
Polymorphism and mutation databases | IARC_TP53; 30040
LiGeA; CCLE_508 Progenetix; CVCL_2255 | ||||||||||||||||||
Entry history | |||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||
Last entry update | 21-Mar-2023 | ||||||||||||||||||
Version number | 24 |