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Cellosaurus Girardi Heart (CVCL_2254)

[Text version]
Cell line name Girardi Heart
Synonyms Girardi heart; GIRARDI HEART
Accession CVCL_2254
Resource Identification Initiative To cite this cell line use: Girardi Heart (RRID:CVCL_2254)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=4864103; PubMed=5641128; PubMed=566722; PubMed=1246601; PubMed=20143388). Originally thought to originate from normal heart cells.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00006.
Population: African American.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Children:
CVCL_1815 (Girardi Heart clone 2)CVCL_1816 (Girardi Heart clone 7)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
STR profile Source(s): IZSLER=BS CL 47

Markers:
AmelogeninX
CSF1PO9,10
D5S81811,12
D7S8208,12
D13S31712,14
D16S5399,10
D21S1127,28
TH017
TPOX8,12
vWA16,18

Run an STR similarity search on this cell line
Web pages Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=13554528; DOI=10.3181/00379727-98-23926
Girardi A.J., Warren J., Goldman C., Jeffries B.
Growth and CF antigenicity of measles virus in cells deriving from human heart.
Proc. Soc. Exp. Biol. Med. 98:18-22(1958)

PubMed=4864103
Gartler S.M.
Genetic markers as tracers in cell culture.
Natl. Cancer Inst. Monogr. 26:167-195(1967)

PubMed=5641128; DOI=10.1038/217750a0
Gartler S.M.
Apparent Hela cell contamination of human heteroploid cell lines.
Nature 217:750-751(1968)

DOI=10.1007/BF02618370
Stulberg C.S., Coriell L.L., Kniazeff A.J., Shannon J.E.
The animal cell culture collection.
In Vitro 5:1-16(1970)

DOI=10.1007/978-1-4757-1647-4_13
Biedler J.L.
Chromosome abnormalities in human tumor cells in culture.
(In book chapter) Human tumor cells in vitro; Fogh J. (eds.); pp.359-394; Springer; New York; USA (1975)

PubMed=1246601; DOI=10.1126/science.1246601
Nelson-Rees W.A., Flandermeyer R.R.
HeLa cultures defined.
Science 191:96-98(1976)

PubMed=566722; DOI=10.1007/BF02616110
Lavappa K.S.
Survey of ATCC stocks of human cell lines for HeLa contamination.
In Vitro 14:469-475(1978)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cross-references
Cell line collections (Providers) ATCC; CCL-27 - Discontinued
ECACC; 93120822
IZSLER; BS CL 47
Cell line databases/resources CLO; CLO_0003495
CLDB; cl1466
CLDB; cl1467
CLDB; cl1468
Biological sample resources BioSample; SAMN03151697
Encyclopedic resources Wikidata; Q54835835
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number24