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Cellosaurus UPCI-SCC-074 (CVCL_2224)

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Cell line name UPCI-SCC-074
Synonyms UPCI:SCC074; UPCISCC074; SCC074
Accession CVCL_2224
Resource Identification Initiative To cite this cell line use: UPCI-SCC-074 (RRID:CVCL_2224)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Indian.
Doubling time: ~60 hours (DSMZ=ACC-664).
Derived from site: In situ; Oral cavity, alveolar ridge; UBERON=UBERON_0004103.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys132Asn (c.396G>T); ClinVar=VCV000634773; Zygosity=Heterozygous (DepMap=ACH-001694).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Heterozygous (DepMap=ACH-001694).
Disease Alveolar ridge squamous cell carcinoma (NCIt: C170774)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 51Y
Category Cancer cell line
STR profile Source(s): DepMap=ACH-001694; DSMZ=ACC-664

Markers:
AmelogeninX
CSF1PO11
D2S133820
D3S135815
D5S81811
D7S8208,11
D8S117910,15
D13S31710,11
D16S5399,10
D18S5116
D19S43313,15
D21S1130.2,31.2
FGA20,24
Penta D6,8
Penta E7,13
TH017,9.3
TPOX9,11
vWA15,17

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Publications

PubMed=17112776; DOI=10.1016/j.oraloncology.2006.09.001; PMCID=PMC2025692
Jason S. White, Joel L. Weissfeld, Camille C.R. Ragin, Karen M. Rossie, Christa Lese Martin, Michele Shuster, Chandramohan S. Ishwad, John C. Law, Eugene Nicholas Myers, Jonas T. Johnson, Susanne M. Gollin;
The influence of clinical and demographic risk factors on the establishment of head and neck squamous cell carcinoma cell lines.
Oral Oncol. 43:701-712(2007)

PubMed=17681875; DOI=10.1016/j.oraloncology.2007.05.003; PMCID=PMC2362065
Christa Lese Martin, Shalini C. Reshmi, Thomas Ried, William Gottberg, John W. Wilson, Jaya K. Reddy, Poornima Khanna, Jonas T. Johnson, Eugene Nicholas Myers, Susanne M. Gollin;
Chromosomal imbalances in oral squamous cell carcinoma: examination of 31 cell lines and review of the literature.
Oral Oncol. 44:369-382(2008)

Cross-references
Cell line collections (Providers) DSMZ; ACC-664
Cell line databases/resources cancercelllines; CVCL_2224
DepMap; ACH-001694
DSMZCellDive; ACC-664
Biological sample resources BioSample; SAMN03473478
Encyclopedic resources Wikidata; Q54991604
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number22