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Cellosaurus PNT2 (CVCL_2164)

[Text version]
Cell line name PNT2
Synonyms PNT 2; PNT-2
Accession CVCL_2164
Resource Identification Initiative To cite this cell line use: PNT2 (RRID:CVCL_2164)
Comments Doubling time: 35.9 +- 1.56 hours (PubMed=21556542).
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pMK16).
Omics: Variations; SNP array analysis.
Derived from site: In situ; Prostate, epithelium; UBERON=UBERON_0000428.
Cell type: Epithelial cell of prostate; CL=CL_0002231.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_JX34 (PNT2 serum free)CVCL_4889 (PNT2-C2)CVCL_W768 (PNT2-LSD)
Sex of cell Male
Age at sampling 33Y
Category Transformed cell line
STR profile Source(s): ECACC=95012613; PubMed=11416159

Markers:
AmelogeninX,Y
CSF1PO11,13
D5S81812,13
D7S82011
D8S117913,14
D13S3178,13
D16S5399
D18S5116,17
D21S1129,33.2
FGA22,24
TH016,9.3
TPOX8,9
vWA17

Run an STR similarity search on this cell line
Web pages Info; ECACC; -; https://www.culturecollections.org.uk/products/cell-cultures/ecacc-cell-line-profiles/pnt2/
Publications

PubMed=21556542; DOI=10.3892/ijo.6.2.333
Philippe Berthon, Olivier Cussenot, Lucy Hopwood, Alain Le Duc, Norman J. Maitland;
Functional expression of SV40 in normal human prostatic epithelial and fibroblastic cells: differentiation pattern of nontumorigenic cell-lines.
Int. J. Oncol. 6:333-343(1995)

PubMed=11135431; DOI=10.1002/1098-2264(2000)9999:9999<::AID-GCC1076>3.0.CO;2-E
Joan Aurich-Costa, Anne Vannier, Eric Gregoire, Frederique Nowak, Dorra Cherif;
IPM-FISH, a new M-FISH approach using IRS-PCR painting probes: application to the analysis of seven human prostate cell lines.
Genes Chromosomes Cancer 30:143-160(2001)

PubMed=11416159; DOI=10.1073/pnas.121616198; PMCID=PMC35459
John R.W. Masters, Jim A. Thomson, Bernadette Daly-Burns, Yvonne A. Reid, Wilhelm Gerhard Dirks, Phil Packer, Lorraine H. Toji, Tadao Ohno, Hideyuki Tanabe, Colin Francis Arlett, Lloyd R. Kelland ...Show all 16 authors... , Maureen Harrison, Arvind K. Virmani, Timothy H. Ward, Karen L. Ayres, Paul G. Debenham; Show fewer authors
Short tandem repeat profiling provides an international reference standard for human cell lines.
Proc. Natl. Acad. Sci. U.S.A. 98:8012-8017(2001)

PubMed=17644708; DOI=10.1099/jmm.0.47241-0
Najwa Al-Mously, Adrian Eley;
Interaction of Chlamydia trachomatis serovar E with male genital tract epithelium results in secretion of proinflammatory cytokines.
J. Med. Microbiol. 56:1025-1032(2007)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662
S. Michael Rothenberg, Gayatry Mohapatra, Miguel N. Rivera, Daniel Winokur, Patricia Greninger, Mai Nitta, Peter M. Sadow, Gaya Sooriyakumar, Brian W. Brannigan, Matthew J. Ulman, Rushika M. Perera ...Show all 22 authors... , Rui Wang, Angela Tam, Xiao-Jun Ma, Mark Erlander, Dennis C. Sgroi, James W. Rocco, Mark W. Lingen, Ezra E.W. Cohen, David Neil Louis, Jeffrey Settleman, Daniel Arie Haber; Show fewer authors
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

Cross-references
Cell line collections (Providers) ECACC; 95012613
Cell line databases/resources CLO; CLO_0008476
CLDB; cl3927
Anatomy/cell type resources BTO; BTO_0002399
Chemistry resources ChEMBL-Cells; CHEMBL4632325
ChEMBL-Targets; CHEMBL4632332
PubChem_Cell_line; CVCL_2164
Encyclopedic resources Wikidata; Q54947682
Experimental variables resources EFO; EFO_0022595
Gene expression databases GEO; GSM827351
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number29