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Cellosaurus NCI-H69/LX10 (CVCL_2138)

[Text version]
Cell line name NCI-H69/LX10
Synonyms H69/LX10
Accession CVCL_2138
Resource Identification Initiative To cite this cell line use: NCI-H69/LX10 (RRID:CVCL_2138)
Comments Selected for resistance to: ChEBI; CHEBI:28748; Doxorubicin (Adriablastin; Adriamycin).
Sequence variations
  • Mutation; HGNC; 8975; PIK3CA; Simple; p.Gly106_Arg108del (c.317_325delGGCAACCGT); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 9884; RB1; Simple; p.Glu748Ter (c.2242G>T); ClinVar=VCV000013078; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Glu171Ter (c.511G>T); ClinVar=VCV000634771; Zygosity=Homozygous (from parent cell line).
Disease Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1579 (NCI-H69)
Sex of cell Male
Age at sampling 55Y
Category Cancer cell line
Cross-references
Cell line collections ECACC; 96042331
Encyclopedic resources Wikidata; Q54908105
Entry history
Entry creation04-Apr-2012
Last entry update15-Dec-2022
Version number17