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Cellosaurus NBL-S (CVCL_2136)

[Text version]
Cell line name NBL-S
Synonyms NBL_S; NBLS
Accession CVCL_2136
Resource Identification Initiative To cite this cell line use: NBL-S (RRID:CVCL_2136)
Comments Doubling time: ~36 hours (DSMZ=ACC-656).
Omics: Genomics; ChIP-seq; H3K27ac.
Omics: Genomics; ChIP-seq; H3K27me3.
Omics: Genomics; ChIP-seq; H3K4me1.
Omics: Genomics; ChIP-seq; H3K4me3.
Omics: Genomics; Chromatin accessibility; ATAC-seq.
Omics: Transcriptomics; RNAseq.
Omics: Variations; Array-based CGH.
Omics: Variations; SNP array analysis.
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 3Y6M
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-656

Markers:
AmelogeninX,Y
CSF1PO11,12
D2S133817,18
D3S135815,17
D5S81811,12
D7S82010
D8S117910,13
D13S31711,13
D16S53910,13
D18S5114,17
D19S43316
D21S1130,33.2
FGA21,22
Penta D11,12
Penta E11,17
TH017
TPOX8,12
vWA18,19

Run an STR similarity search on this cell line
Publications

DOI=10.1007/0-306-46872-7_2
Thiele C.J.
Neuroblastoma.
(In book chapter) Human cell culture. Vol. 1. Cancer cell lines part 1; Masters J.R.W., Palsson B.O. (eds.); pp.21-53; Kluwer Academic Publishers; New York; USA (1999)

PubMed=11550280; DOI=10.1002/gcc.1174
Van Roy N., Van Limbergen H., Vandesompele J., Van Gele M., Poppe B., Salwen H.R., Laureys G., Manoel N., De Paepe A., Speleman F.
Combined M-FISH and CGH analysis allows comprehensive description of genetic alterations in neuroblastoma cell lines.
Genes Chromosomes Cancer 32:126-135(2001)

PubMed=15892104; DOI=10.1002/gcc.20198
Mosse Y.P., Greshock J., Margolin A.A., Naylor T., Cole K.A., Khazi D., Hii G., Winter C., Shahzad S., Asziz M.U., Biegel J.A., Weber B.L., Maris J.M.
High-resolution detection and mapping of genomic DNA alterations in neuroblastoma.
Genes Chromosomes Cancer 43:390-403(2005)

PubMed=16822308; DOI=10.1186/1471-2407-6-177; PMCID=PMC1533846
Dam V., Morgan B.T., Mazanek P., Hogarty M.D.
Mutations in PIK3CA are infrequent in neuroblastoma.
BMC Cancer 6:177.1-177.10(2006)

PubMed=18724359; DOI=10.1038/nature07261; PMCID=PMC2672043
Mosse Y.P., Laudenslager M., Longo L., Cole K.A., Wood A., Attiyeh E.F., Laquaglia M.J., Sennett R., Lynch J.E., Perri P., Laureys G., Speleman F., Kim C., Hou C.-P., Hakonarson H., Torkamani A., Schork N.J., Brodeur G.M., Tonini G.P., Rappaport E., Devoto M., Maris J.M.
Identification of ALK as a major familial neuroblastoma predisposition gene.
Nature 455:930-935(2008)

PubMed=23202128; DOI=10.1038/ng.2493; PMCID=PMC3557959
Sausen M., Leary R.J., Jones S., Wu J., Reynolds C.P., Liu X.-Y., Blackford A.L., Parmigiani G., Diaz L.A. Jr., Papadopoulos N., Vogelstein B., Kinzler K.W., Velculescu V.E., Hogarty M.D.
Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma.
Nat. Genet. 45:12-17(2013)

PubMed=28350380; DOI=10.1038/sdata.2017.33; PMCID=PMC5369315
Harenza J.L., Diamond M.A., Adams R.N., Song M.M., Davidson H.L., Hart L.S., Dent M.H., Fortina P., Reynolds C.P., Maris J.M.
Transcriptomic profiling of 39 commonly-used neuroblastoma cell lines.
Sci. Data 4:170033.1-170033.8(2017)

Cross-references
Cell line collections (Providers) DSMZ; ACC-656
Cell line databases/resources DSMZCellDive; ACC-656
Biological sample resources BioSample; SAMN03473469
Encyclopedic resources Wikidata; Q54907552
Gene expression databases GEO; GSM2371248
GEO; GSM2394377
GEO; GSM4104587
GEO; GSM4104588
GEO; GSM4105328
GEO; GSM4105329
GEO; GSM4105330
GEO; GSM4105331
GEO; GSM4105332
Polymorphism and mutation databases Cosmic; 848930
Cosmic; 923829
Cosmic; 930070
Cosmic; 1019947
Cosmic; 1109367
Cosmic; 1161997
Cosmic; 1167414
Cosmic; 1526636
IARC_TP53; 23593
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number20