Cellosaurus logo
expasy logo

Cellosaurus MUTZ-8 (CVCL_2130)

[Text][XML][JSON]
Cell line name MUTZ-8
Synonyms MUTZ8; Menschliche Und Tierische Zellkulture-8
Accession CVCL_2130
Resource Identification Initiative To cite this cell line use: MUTZ-8 (RRID:CVCL_2130)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Characteristics: Cytokines dependent (PubMed=12145698).
Doubling time: ~5 days (DOI=10.1007/978-3-642-59358-1_22); ~3-5 days (DSMZ=ACC-689).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
Disease Adult acute myelomonocytic leukemia (NCIt: C7962)
Acute myelomonocytic leukemia (ORDO: Orphanet_517)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 63Y
Category Cancer cell line
STR profile Source(s): DepMap=ACH-001577; DSMZ=ACC-689

Markers:
AmelogeninX
CSF1PO11
D2S133817,23
D3S135816
D5S81812
D7S82011
D8S117914
D13S3179,11
D16S53912
D18S5112,15
D19S43313,15
D21S1128,29
FGA18,20
Penta D13,15
Penta E12,20
TH019,9.3
TPOX8,9
vWA18

Run an STR similarity search on this cell line
Web pages Info; COPE; -; http://www.cells-talk.com/index.php/page/copelibrary?key=MUTZ-8
Publications

PubMed=12145698; DOI=10.1038/sj.leu.2402601
Zhen-Bo Hu, Roderick A.F. MacLeod, Corinna Meyer, Hilmar Quentmeier, Hans Gunther Drexler;
New acute myeloid leukemia-derived cell line: MUTZ-8 with 5q-.
Leukemia 16:1556-1561(2002)

DOI=10.1007/978-3-642-59358-1_22
Zhen-Bo Hu, Hilmar Quentmeier, Corinna Meyer, Roderick A.F. MacLeod, Hans Gunther Drexler;
Establishment of the two cytokine-dependent acute myeloid leukemia-derived cell lines MUTZ-8 and MUTZ-11.
(In book chapter) Acute leukemias IX. Haematology and blood transfusion, Vol. 41; Hiddemann, Wolfgang & Haferlach, Torsten & Unterhalt, Michael & Buchner, Thomas & Ritter, Jorg (eds.); pp.122-127; Springer; Berlin; Germany (2003)

PubMed=16408098; DOI=10.1038/sj.leu.2404081
Hilmar Quentmeier, Roderick A.F. MacLeod, Margarete Zaborski, Hans Gunther Drexler;
JAK2 V617F tyrosine kinase mutation in cell lines derived from myeloproliferative disorders.
Leukemia 20:471-476(2006)

PubMed=36982453; DOI=10.3390/ijms24065377; PMCID=PMC10049680
Rafal Skopek, Malgorzata Palusinska, Katarzyna Kaczor-Keller, Rafal Pingwara, Anna Papierniak-Wygladala, Tino Schenk, Slawomir Lewicki, Artur Zelent, Lukasz Szymanski;
Choosing the right cell line for acute myeloid leukemia (AML) research.
Int. J. Mol. Sci. 24:5377.1-5377.34(2023)

Cross-references
Cell line collections (Providers) DSMZ; ACC-689
Cell line databases/resources cancercelllines; CVCL_2130
DepMap; ACH-001577
DSMZCellDive; ACC-689
Anatomy/cell type resources BTO; BTO_0004768
Encyclopedic resources Wikidata; Q54907104
Polymorphism and mutation databases Cosmic; 975282
Cosmic; 1012053
Cosmic; 1281339
Cosmic; 1465960
Cosmic; 2306225
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number29