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Cellosaurus MOLM-20 (CVCL_2121)

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Cell line name MOLM-20
Synonyms MOLM20
Accession CVCL_2121
Resource Identification Initiative To cite this cell line use: MOLM-20 (RRID:CVCL_2121)
Comments Part of: LL-100 blood cancer cell line panel.
Population: Japanese.
Doubling time: ~70 hours (DSMZ=ACC-591).
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene fusion; HGNC; HGNC:7132; KMT2A + HGNC; HGNC:25589; SEPTIN11; Name(s)=KMT2A-SEPTIN11, KMT2A-SEPT11, MLL-SEPT11 (PubMed=31160637; DSMZ=ACC-591).
HLA typing Source: DSMZCellDive=ACC-591
Class I
HLA-AA*26:02:01,26:03:01
HLA-BB*15:01:01,40:06:01
HLA-CC*03:03:01,08:01:01
Class II
HLA-DPDPA1*01:03:01,01:03:01
DPB1*02:01:02,02:01:02
HLA-DRDRA*01:01:01,01:01:01
DRB1*09:01:02,09:01:02
Disease Chronic neutrophilic leukemia (NCIt: C3179)
Chronic neutrophilic leukemia (ORDO: Orphanet_86829)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_V650 ! CNLBC1
Sex of cell Female
Age at sampling 63Y
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-591

Markers:
AmelogeninX
CSF1PO11,12
D2S133817,19
D3S135815
D5S81811
D7S82010,11
D8S117910
D13S3178,11
D16S53913
D18S5114,15
D19S43312,14
D21S1129,30
FGA21,22
Penta D10,12
Penta E8,12
TH016
TPOX9,11
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=16408098; DOI=10.1038/sj.leu.2404081
Hilmar Quentmeier, Roderick A.F. MacLeod, Margarete Zaborski, Hans Gunther Drexler;
JAK2 V617F tyrosine kinase mutation in cell lines derived from myeloproliferative disorders.
Leukemia 20:471-476(2006)

PubMed=31160637; DOI=10.1038/s41598-019-44491-x; PMCID=PMC6547646
Hilmar Quentmeier, Claudia Pommerenke, Wilhelm Gerhard Dirks, Sonja Eberth, Max Koeppel, Roderick A.F. MacLeod, Stefan Nagel, Klaus G. Steube, Cord C. Uphoff, Hans Gunther Drexler;
The LL-100 panel: 100 cell lines for blood cancer studies.
Sci. Rep. 9:8218.1-8218.14(2019)

Cross-references
Cell line collections (Providers) DSMZ; ACC-591
Cell line databases/resources DSMZCellDive; ACC-591
Biological sample resources BioSample; SAMN03473490
Encyclopedic resources Wikidata; Q54906328
Gene expression databases ArrayExpress; E-MTAB-7721
ArrayExpress; E-MTAB-7722
Polymorphism and mutation databases Cosmic; 1012098
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number25