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Cellosaurus HROC278 T0 M1 (CVCL_1U89)

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Cell line name HROC278 T0 M1
Synonyms HROC278
Accession CVCL_1U89
Resource Identification Initiative To cite this cell line use: HROC278 T0 M1 (RRID:CVCL_1U89)
Comments From: Linnebacher, Michael; University of Rostock; Rostock; Germany.
Population: Caucasian.
Characteristics: Established from a patient-derived xenograft established in female NMRI nu/nu mice.
Doubling time: 43 hours (CLS=300835).
Microsatellite instability: Instable (MSI-low) (Direct_author_submission).
Derived from site: In situ; Colon, ascending; UBERON=UBERON_0001156.
HLA typing Source: Direct_author_submission
Class I
HLA-AA*03:01,25:01
HLA-BB*07:02,18:01
HLA-CC*07:02,12:03
Class II
HLA-DQDQB1*03:02,03:02
HLA-DRDRB1*04:01,04:01

Source: CLS=300835
Class I
HLA-AA*03:01:01,01:01:01
HLA-BB*07:02:01,18:01:01
HLA-CC*07:02:01,12:03:01
Class II
HLA-DPDPB1*02:01
HLA-DQDQA1*03:01:01
DQB1*03:02:01
HLA-DRDRB1*04:01:01
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_A7UL ! B-LCL-HROC278
CVCL_1U90 ! HROC278Met T2 M2
Sex of cell Female
Age at sampling 76Y
Category Cancer cell line
STR profile Source(s): CLS=300835; Direct_author_submission

Markers:
AmelogeninX
CSF1PO10
D5S81813
D7S82011,12
D13S31710
D16S53912,13
TH017,9
TPOX11
vWA14,18

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Publications

PubMed=31601052; DOI=10.3390/cancers11101520; PMCID=PMC6826890
Christina Susanne Mullins, Bianca Micheel, Stephanie Matschos, Matthias Leuchter, Florian Burtin, Mathias Krohn, Maja Huhns, Ernst Klar, Friedrich Prall, Michael Linnebacher;
Integrated biobanking and tumor model establishment of human colorectal carcinoma provides excellent tools for preclinical research.
Cancers (Basel) 11:1520.1-1520.18(2019)

Cross-references
Cell line collections (Providers) CLS; 300835
Encyclopedic resources Wikidata; Q54895264
Entry history
Entry creation08-Jul-2015
Last entry update10-Sep-2024
Version number18