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Cellosaurus SK-MEL-426 (CVCL_1T75)

[Text version]
Cell line name SK-MEL-426
Synonyms SK-Mel-426
Accession CVCL_1T75
Resource Identification Initiative To cite this cell line use: SK-MEL-426 (RRID:CVCL_1T75)
Comments From: Memorial Sloan Kettering Cancer Center; New York; USA.
Sequence variations
  • Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=24576830).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Cancer cell line
Publications

PubMed=24576830; DOI=10.1158/0008-5472.CAN-13-2625
Nissan M.H., Pratilas C.A., Jones A.M., Ramirez R., Won H., Liu C.-L., Tiwari S., Kong L., Hanrahan A.J., Yao Z., Merghoub T., Ribas A., Chapman P.B., Yaeger R., Taylor B.S., Schultz N., Berger M.F., Rosen N., Solit D.B.
Loss of NF1 in cutaneous melanoma is associated with RAS activation and MEK dependence.
Cancer Res. 74:2340-2350(2014)

Cross-references
Cell line databases/resources cancercelllines; CVCL_1T75
Encyclopedic resources Wikidata; Q54954170
Entry history
Entry creation08-Jul-2015
Last entry update05-Oct-2023
Version number9