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Cellosaurus DT40-RAD54L(-/-) (CVCL_1T34)

[Text version]
Cell line name DT40-RAD54L(-/-)
Synonyms RAD54-/- DT40; Delta-Rad54-DT40
Accession CVCL_1T34
Resource Identification Initiative To cite this cell line use: DT40-RAD54L(-/-) (RRID:CVCL_1T34)
Comments Group: Bird cell line.
Knockout cell: Method=Targeted integration; CGNC; 7881; RAD54L.
Transformant: NCBI_TaxID; 11864; Avian leukosis virus (ALV).
Cell type: B-cell; CL=CL_0000236.
Disease Chicken bursal lymphoma (NCIt: C134556)
Species of origin Gallus gallus (Chicken) (NCBI Taxonomy: 9031)
Breed/subspecies: Hy-Line SC.
Hierarchy Parent: CVCL_J437 (DT40 CL18)
Children:
CVCL_LH54 (DT40-ATM(-/-)-RAD5L(-/-) hRad54)
Sex of cell Female
Age at sampling 1D
Category Cancer cell line
Publications

PubMed=9108474; DOI=10.1016/S0092-8674(00)80198-1
Olga Bezzubova, Arkadiy Silbergleit, Yuko Yamaguchi-Iwai, Shunichi Takeda, Jean-Marie Buerstedde;
Reduced X-ray resistance and homologous recombination frequencies in a RAD54-/- mutant of the chicken DT40 cell line.
Cell 89:185-193(1997)

PubMed=10938124; DOI=10.1128/mcb.20.17.6476-6482.2000; PMCID=PMC86122
Minoru Takata, Masao S. Sasaki, Eiichiro Sonoda, Toru Fukushima, Ciaran Morrison, Joanna S. Albala, Sigrid M.A. Swagemakers, Roland Kanaar, Lawrence H. Thompson, Shunichi Takeda;
The Rad51 paralog Rad51B promotes homologous recombinational repair.
Mol. Cell. Biol. 20:6476-6482(2000)

Cross-references
Cell line collections (Providers) RCB; RCB1628
Cell line databases/resources CLO; CLO_0051468
Encyclopedic resources Wikidata; Q54831526
Entry history
Entry creation08-Jul-2015
Last entry update10-Sep-2024
Version number12