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Cellosaurus H7D7BD5 (CVCL_1T10)

[Text version]
Cell line name H7D7BD5
Synonyms H7D7-BD5; BD5; HepG2-BD5
Accession CVCL_1T10
Resource Identification Initiative To cite this cell line use: H7D7BD5 (RRID:CVCL_1T10)
Comments Problematic cell line: Contaminated. Parent cell line (H7D7B) has been shown to be a Hep-G2 derivative (PubMed=12619888).
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00560.
Population: Caucasian.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1T07 (H7D7B)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx

PubMed=12619888; DOI=10.1023/A:1021653506123
van Pelt J.F., Decorte R., Yap P.S.H., Fevery J.
Identification of HepG2 variant cell lines by short tandem repeat (STR) analysis.
Mol. Cell. Biochem. 243:49-54(2003)

Cell line databases/resources cancercelllines; CVCL_1T10
Encyclopedic resources Wikidata; Q54872222
Entry history
Entry creation08-Jul-2015
Last entry update02-May-2024
Version number18