Cellosaurus cell line KM3 [Contaminated human melanoma] (CVCL

Cellosaurus KM3 [Contaminated human melanoma] (CVCL_1R51)

Cross-references
Cell line name	KM3 [Contaminated human melanoma]
Synonyms	Mel-Km3; Km3
Accession	CVCL_1R51
Resource Identification Initiative	To cite this cell line use: KM3 [Contaminated human melanoma] (RRID:CVCL_1R51)
Comments	Problematic cell line: Misidentified. Originally thought to be of human origin (astrocytoma) but found to be from rat (PubMed=12740908; PubMed=20143388). Originally thought to originate from a woman patient lymph nodes metastases of a melanoma. Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00227.
Species of origin	Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Sex of cell	Sex unspecified
Age at sampling	Age unspecified
Category	Undefined cell line type
Web pages	https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx
Publications	PubMed=7520026; DOI=10.1002/ijc.2910580413 Hersey P., Si Z.-Y., Smith M.J., Thomas W.D. Expression of the co-stimulatory molecule B7 on melanoma cells. Int. J. Cancer 58:527-532(1994) PubMed=8980186; DOI=10.1002/(SICI)1097-0215(19961211)68:6<795::AID-IJC18>3.0.CO;2-# Thomas W.D., Smith M.J., Si Z.-Y., Hersey P. Expression of the co-stimulatory molecule CD40 on melanoma cells. Int. J. Cancer 68:795-801(1996) PubMed=9120293; DOI=10.4049/jimmunol.158.7.3353 Radford K.J., Thorne R.F., Hersey P. Regulation of tumor cell motility and migration by CD63 in a human melanoma cell line. J. Immunol. 158:3353-3358(1997) PubMed=12740908; DOI=10.1002/ijc.11144 Moseley G.W., Elliott J., Wright M.D., Partridge L.J., Monk P.N. Interspecies contamination of the KM3 cell line: implications for CD63 function in melanoma metastasis. Int. J. Cancer 105:613-616(2003) PubMed=20143388; DOI=10.1002/ijc.25242 Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I. Check your cultures! A list of cross-contaminated or misidentified cell lines. Int. J. Cancer 127:1-8(2010)
Biological sample resources	BioSample; SAMN03151998
Encyclopedic resources	Wikidata; Q54900068
Entry history
Entry creation	08-Jul-2015
Last entry update	21-Mar-2023
Version number	12