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Cellosaurus NP-2/CD4/CCR3 (CVCL_1R26)

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Cell line name NP-2/CD4/CCR3
Accession CVCL_1R26
Resource Identification Initiative To cite this cell line use: NP-2/CD4/CCR3 (RRID:CVCL_1R26)
Comments Population: Japanese.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:1604; CCR3.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:1678; CD4.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Brain, left frontal lobe; UBERON=UBERON_0002811.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Met237Ile (c.711G>T); ClinVar=VCV000634770; Zygosity=Unspecified (from parent cell line).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1R18 (NP-2/CD4)
Sex of cell Male
Age at sampling 63Y
Category Cancer cell line
Publications

PubMed=11112502; DOI=10.1006/viro.2000.0623
Hui-Yu Liu, Yasushi Soda, Nobuaki Shimizu, Yuji Haraguchi, Atsushi Jinno-Oue, Yasuhiro Takeuchi, Hiroo Hoshino;
CD4-dependent and CD4-independent utilization of coreceptors by human immunodeficiency viruses type 2 and simian immunodeficiency viruses.
Virology 278:276-288(2000)

DOI=10.2974/kmj.62.1
Hiroo Hoshino;
The NP-2 cell system for analyses of the coreceptor usage of human and simian immunodeficiency viruses.
Kitakanto Med. J. 62:1-14(2012)

Cross-references
Cell line databases/resources cancercelllines; CVCL_1R26
Encyclopedic resources Wikidata; Q54930947
Entry history
Entry creation08-Jul-2015
Last entry update14-Aug-2025
Version number14