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Cellosaurus H414-RAD18(+/-) (CVCL_1Q98)
[Text version]
| Cell line name |
H414-RAD18(+/-)
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| Accession |
CVCL_1Q98
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| Resource Identification Initiative |
To cite this cell line use: H414-RAD18(+/-) (RRID:CVCL_1Q98) |
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| Comments |
Knockout cell: Method=Homologous recombination (1 of 2 alleles); HGNC; 18278; RAD18.
Derived from sampling site: Colon.
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| Sequence variations |
- Mutation; HGNC; 173; ACVR2A; Simple; p.Lys437Argfs*5 (c.1310delA); dbSNP=rs764719749; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; 1101; BRCA2; Simple; p.Ile2675Aspfs*6 (c.8021dupA) (c.8021_8022insA); ClinVar=VCV000267050; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 1787; CDKN2A; Simple; p.Arg24Serfs*20 (c.68dupG) (c.68_69insG) (p.G23fs); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 2514; CTNNB1; Simple; p.Ser45del (c.133_135delTCT); ClinVar=VCV000017576; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 3373; EP300; Simple; p.Met1470Cysfs*22 (c.4408delA); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 3373; EP300; Simple; p.Asn1700Thrfs*9 (c.5099delA); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 6407; KRAS; Simple; p.Gly13Asp (c.38G>A); ClinVar=VCV000012580; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 11773; TGFBR2; Simple; p.Lys128Serfs*35 (c.383delA); ClinVar=VCV000477546; Zygosity=Homozygous (from parent cell line).
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| Disease |
Colon carcinoma (NCIt: C4910)
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606)
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| Hierarchy |
Parent: CVCL_1Q94 (H414)
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| Sex of cell |
Male
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| Age at sampling |
48Y
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| Category |
Cancer cell line
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| Cross-references |
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| Cell line collections |
RCB; RCB2998
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| Encyclopedic resources |
Wikidata; Q54872143
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| Entry history |
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| Entry creation | 08-Jul-2015 |
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| Last entry update | 20-May-2021 |
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| Version number | 9 |
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