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Cellosaurus T409 (CVCL_1Q88)

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Cell line name T409
Synonyms T-409
Accession CVCL_1Q88
Resource Identification Initiative To cite this cell line use: T409 (RRID:CVCL_1Q88)
Comments Problematic cell line: Contaminated. Shown to be a UM-SCC-1 derivative (PubMed=21868764).
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00427.
Population: Caucasian.
Derived from site: In situ; Oral cavity, floor of mouth; UBERON=UBERON_0003679.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (from parent cell line).
Disease Floor of mouth squamous cell carcinoma (NCIt: C4041)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_7707 (UM-SCC-1)
Sex of cell Male
Age at sampling 72Y
Category Cancer cell line
STR profile Source(s): PubMed=21868764

Markers:
AmelogeninX
CSF1PO10,12
D5S81810,13
D7S8209,12
D13S3178,11
D16S53912,13
TH016
TPOX8,11
vWA15,18

Run an STR similarity search on this cell line
Web pages Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=18234965; DOI=10.1158/1541-7786.MCR-07-0221
Mohammed Momin Shareef, Brandee Brown, Shahin Shajahan, Sabapathi Sathishkumar, Susanne M. Arnold, Mohammed Mohiuddin, Mansoor M. Ahmed, Paul M. Spring;
Lack of P-glycoprotein expression by low-dose fractionated radiation results from loss of nuclear factor-kappaB and NF-Y activation in oral carcinoma cells.
Mol. Cancer Res. 6:89-98(2008)

PubMed=21868764; DOI=10.1158/1078-0432.CCR-11-0690; PMCID=PMC3229662
Mei Zhao, Daisuke Sano, Curtis R. Pickering, Samar A. Jasser, Ying C. Henderson, Gary L. Clayman, Erich M. Sturgis, Thomas J. Ow, Reuben Lotan, Thomas E. Carey, Peter G. Sacks ...Show all 15 authors... , Jennifer Rubin Grandis, David Sidransky, Nils-Erik Heldin, Jeffrey N. Myers; Show fewer authors
Assembly and initial characterization of a panel of 85 genomically validated cell lines from diverse head and neck tumor sites.
Clin. Cancer Res. 17:7248-7264(2011)

Cross-references
Biological sample resources BioSample; SAMN03151991
Encyclopedic resources Wikidata; Q54971556
Polymorphism and mutation databases Cosmic; 1530764
Entry history
Entry creation08-Jul-2015
Last entry update10-Apr-2025
Version number20