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Cellosaurus T409 (CVCL_1Q88)

[Text version]
Cell line name T409
Synonyms T-409
Accession CVCL_1Q88
Resource Identification Initiative To cite this cell line use: T409 (RRID:CVCL_1Q88)
Comments Problematic cell line: Contaminated. Shown to be a UM-SCC-1 derivative (PubMed=21868764).
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00427.
Population: Caucasian.
Derived from site: In situ; Oral cavity, floor of mouth; UBERON=UBERON_0003679.
Sequence variations
  • Mutation; HGNC; 11998; TP53; None_reported; -; Zygosity=- (from parent cell line).
Disease Floor of mouth squamous cell carcinoma (NCIt: C4041)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_7707 (UM-SCC-1)
Sex of cell Male
Age at sampling 72Y
Category Cancer cell line
STR profile Source(s): PubMed=21868764


Run an STR similarity search on this cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx

PubMed=18234965; DOI=10.1158/1541-7786.MCR-07-0221
Shareef M.M., Brown B., Shajahan S., Sathishkumar S., Arnold S.M., Mohiuddin M., Ahmed M.M., Spring P.M.
Lack of P-glycoprotein expression by low-dose fractionated radiation results from loss of nuclear factor-kappaB and NF-Y activation in oral carcinoma cells.
Mol. Cancer Res. 6:89-98(2008)

PubMed=21868764; DOI=10.1158/1078-0432.CCR-11-0690
Zhao M., Sano D., Pickering C.R., Jasser S.A., Henderson Y.C., Clayman G.L., Sturgis E.M., Ow T.J., Lotan R., Carey T.E., Sacks P.G., Grandis J.R., Sidransky D., Heldin N.-E., Myers J.N.
Assembly and initial characterization of a panel of 85 genomically validated cell lines from diverse head and neck tumor sites.
Clin. Cancer Res. 17:7248-7264(2011)

Biological sample resources BioSample; SAMN03151991
Encyclopedic resources Wikidata; Q54971556
Polymorphism and mutation databases Cosmic; 1530764
Entry history
Entry creation08-Jul-2015
Last entry update30-Jan-2024
Version number17