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Cellosaurus HepG2/C3A-2.5B1 (CVCL_1N69)

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Cell line name HepG2/C3A-2.5B1
Synonyms C3A clone 2.5B1; Clone 2.5 B1
Accession CVCL_1N69
Resource Identification Initiative To cite this cell line use: HepG2/C3A-2.5B1 (RRID:CVCL_1N69)
Comments Group: Patented cell line.
Group: Serum/protein free medium cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-12461.
Population: Caucasian.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1098 (Hep-G2/C3A)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line
Publications

Patent=US6653105
Dennis Triglia, Anthony F. Purchio;
Clonal cells and cell lines derived from C3A cells and methods of making and using them.
Patent number US6653105, 25-Nov-2003

Cross-references
Cell line collections (Providers) ATCC; CRL-3533
Cell line databases/resources cancercelllines; CVCL_1N69
Encyclopedic resources Wikidata; Q54808152
Entry history
Entry creation08-Jul-2015
Last entry update19-Dec-2024
Version number15