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Cellosaurus irs1 (CVCL_1N51)

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Cell line name irs1
Synonyms irs 1; irs-1
Accession CVCL_1N51
Resource Identification Initiative To cite this cell line use: irs1 (RRID:CVCL_1N51)
Comments Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Cell type: Fibroblast of lung; CL=CL_0002553.
Sequence variations
  • Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line).
  • Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_2796 (V79-4)
Children:
CVCL_1S04 (GM10791)CVCL_DE47 (GM11619)CVCL_1S33 (GM11691)
CVCL_1S34 (GM11692)CVCL_1S72 (GM13412)
Sex of cell Male
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=3106801; DOI=10.1016/0167-8817(87)90011-3
Nigel J. Jones, Roger Cox, John Thacker;
Isolation and cross-sensitivity of X-ray-sensitive mutants of V79-4 hamster cells.
Mutat. Res. 183:279-286(1987)

PubMed=2158612; DOI=10.1093/mutage/5.1.15
Nigel J. Jones, Sheila A. Stewart, Lawrence H. Thompson;
Biochemical and genetic analysis of the Chinese hamster mutants irs1 and irs2 and their comparison to cultured ataxia telangiectasia cells.
Mutagenesis 5:15-23(1990)

Cross-references
Encyclopedic resources Wikidata; Q54898258
Entry history
Entry creation08-Jul-2015
Last entry update29-Jun-2023
Version number10