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Cellosaurus PBS-12SF (CVCL_1K17)

[Text version]
Cell line name PBS-12SF
Synonyms PBS-12 SF; PBS12SF
Accession CVCL_1K17
Resource Identification Initiative To cite this cell line use: PBS-12SF (RRID:CVCL_1K17)
Comments Group: Bird cell line.
Group: Patented cell line.
Group: Serum/protein free medium cell line.
Group: Vaccine production cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); PTA-8565.
Transformant: ChEBI; CHEBI:21759; N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).
Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Gallus gallus (Chicken) (NCBI Taxonomy: 9031)
Hierarchy Parent: CVCL_1K16 (PBS-1)
Sex of cell Sex unspecified
Age at sampling 11FD
Category Transformed cell line

PubMed=18524432; DOI=10.1016/j.vaccine.2008.04.048
Smith K.A., Colvin C.J., Weber P.S.D., Spatz S.J., Coussens P.M.
High titer growth of human and avian influenza viruses in an immortalized chick embryo cell line without the need for exogenous proteases.
Vaccine 26:3778-3782(2008)

PubMed=21911025; DOI=10.1016/j.vaccine.2011.08.122
Coussens P.M., Smith K.A., Weber P.S.D., Colvin C.J.
Immortalized chick embryo cell line adapted to serum-free growth conditions and capable of replicating human and reassortant H5N1 influenza strains for vaccine production.
Vaccine 29:8661-8668(2011)

Coussens P.M., Smith K.A., Weber P.S.D.
Immortal avian cell line and methods of use.
Patent number US8716016, 06-May-2014

PubMed=25903999; DOI=10.1002/biot.201400388
Genzel Y.
Designing cell lines for viral vaccine production: where do we stand?
Biotechnol. J. 10:728-740(2015)

Sporer K.R.B., Carter J.L., Coussens P.M.
The PBS-12SF cell line: development of an alternative cell line for influenza vaccine production.
J. Vaccines Vaccin. 7:345-345(2016)

Cell line databases/resources FCS-free; 212-28-432-1-6
FCS-free; 212-28-432-1-16-12
Encyclopedic resources Wikidata; Q54938373
Entry history
Entry creation08-Jul-2015
Last entry update29-Jun-2023
Version number14