Cellosaurus cell line PBS-12SF (CVCL

Cellosaurus PBS-12SF (CVCL_1K17)

Cross-references
Cell line name	PBS-12SF
Synonyms	PBS-12 SF; PBS12SF
Accession	CVCL_1K17
Resource Identification Initiative	To cite this cell line use: PBS-12SF (RRID:CVCL_1K17)
Comments	Group: Bird cell line. Group: Patented cell line. Group: Serum/protein free medium cell line. Group: Vaccine production cell line. Registration: International Depositary Authority, American Type Culture Collection (ATCC); PTA-8565. Transformant: ChEBI; CHEBI_21759; N-methyl-N'-nitro-N-nitrosoguanidine (MNNG). Derived from site: In situ; Embryo; UBERON=UBERON_0000922. Cell type: Fibroblast; CL=CL_0000057.
Species of origin	Gallus gallus (Chicken) (NCBI Taxonomy: 9031)
Hierarchy	Parent: CVCL_1K16 (PBS-1)
Sex of cell	Sex unspecified
Age at sampling	11FD
Category	Transformed cell line
Web pages	Provider; MSUT; TEC2007-0090; http://msut.technologypublisher.com/technology/7783
Publications	PubMed=18524432; DOI=10.1016/j.vaccine.2008.04.048 Kristen Ann Smith, Christopher J. Colvin, Patty Sue Dickerson Weber, Stephen J. Spatz, Paul Michael Coussens; High titer growth of human and avian influenza viruses in an immortalized chick embryo cell line without the need for exogenous proteases. Vaccine 26:3778-3782(2008) PubMed=21911025; DOI=10.1016/j.vaccine.2011.08.122 Paul Michael Coussens, Kristen Ann Smith, Patty Sue Dickerson Weber, Christopher J. Colvin; Immortalized chick embryo cell line adapted to serum-free growth conditions and capable of replicating human and reassortant H5N1 influenza strains for vaccine production. Vaccine 29:8661-8668(2011) Patent=US8716016 Paul Michael Coussens, Kristen Ann Smith, Patty Sue Dickerson Weber; Immortal avian cell line and methods of use. Patent number US8716016, 06-May-2014 PubMed=25903999; DOI=10.1002/biot.201400388 Yvonne Genzel; Designing cell lines for viral vaccine production: where do we stand? Biotechnol. J. 10:728-740(2015) DOI=10.4172/2157-7560.1000345 Kelly R.B. Sporer, Jenna L. Carter, Paul Michael Coussens; The PBS-12SF cell line: development of an alternative cell line for influenza vaccine production. J. Vaccines Vaccin. 7:345-345(2016)
Cell line databases/resources	FCS-free; 212-28-432-1-16-12 FCS-free; 212-28-432-1-6
Encyclopedic resources	Wikidata; Q54938373
Entry history
Entry creation	08-Jul-2015
Last entry update	10-Apr-2025
Version number	16