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Cellosaurus PBS-12SF (CVCL_1K17)

[Text version]
Cell line name PBS-12SF
Synonyms PBS-12 SF; PBS12SF
Accession CVCL_1K17
Resource Identification Initiative To cite this cell line use: PBS-12SF (RRID:CVCL_1K17)
Comments Group: Bird cell line.
Group: Patented cell line.
Group: Serum/protein free medium cell line.
Group: Vaccine production cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); PTA-8565.
Transformant: ChEBI; CHEBI_21759; N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).
Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Gallus gallus (Chicken) (NCBI Taxonomy: 9031)
Hierarchy Parent: CVCL_1K16 (PBS-1)
Sex of cell Sex unspecified
Age at sampling 11FD
Category Transformed cell line
Web pages Provider; MSUT; TEC2007-0090; http://msut.technologypublisher.com/technology/7783
Publications

PubMed=18524432; DOI=10.1016/j.vaccine.2008.04.048
Kristen Ann Smith, Christopher J. Colvin, Patty Sue Dickerson Weber, Stephen J. Spatz, Paul Michael Coussens;
High titer growth of human and avian influenza viruses in an immortalized chick embryo cell line without the need for exogenous proteases.
Vaccine 26:3778-3782(2008)

PubMed=21911025; DOI=10.1016/j.vaccine.2011.08.122
Paul Michael Coussens, Kristen Ann Smith, Patty Sue Dickerson Weber, Christopher J. Colvin;
Immortalized chick embryo cell line adapted to serum-free growth conditions and capable of replicating human and reassortant H5N1 influenza strains for vaccine production.
Vaccine 29:8661-8668(2011)

Patent=US8716016
Paul Michael Coussens, Kristen Ann Smith, Patty Sue Dickerson Weber;
Immortal avian cell line and methods of use.
Patent number US8716016, 06-May-2014

PubMed=25903999; DOI=10.1002/biot.201400388
Yvonne Genzel;
Designing cell lines for viral vaccine production: where do we stand?
Biotechnol. J. 10:728-740(2015)

DOI=10.4172/2157-7560.1000345
Kelly R.B. Sporer, Jenna L. Carter, Paul Michael Coussens;
The PBS-12SF cell line: development of an alternative cell line for influenza vaccine production.
J. Vaccines Vaccin. 7:345-345(2016)

Cross-references
Cell line databases/resources FCS-free; 212-28-432-1-16-12
FCS-free; 212-28-432-1-6
Encyclopedic resources Wikidata; Q54938373
Entry history
Entry creation08-Jul-2015
Last entry update10-Apr-2025
Version number16