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Cellosaurus T47D-Y (CVCL_1H30)

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Cell line name T47D-Y
Accession CVCL_1H30
Resource Identification Initiative To cite this cell line use: T47D-Y (RRID:CVCL_1H30)
Comments Population: Caucasian.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Leu194Phe (c.580C>T); ClinVar=VCV000127817; Zygosity=Homozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0553 (T-47D)
Children:
CVCL_1H31 (T47D-YA)CVCL_1H32 (T47D-YB)
Sex of cell Female
Age at sampling 54Y
Category Cancer cell line
Publications

PubMed=8033109
Carol A. Sartorius, Steve D. Groshong, Louise A. Miller, Roger L. Powell, Lin Tung, Glenn S. Takimoto, Kathryn Bloch Horwitz;
New T47D breast cancer cell lines for the independent study of progesterone B- and A-receptors: only antiprogestin-occupied B-receptors are switched to transcriptional agonists by cAMP.
Cancer Res. 54:3868-3877(1994)

Cross-references
Cell line databases/resources cancercelllines; CVCL_1H30
TOKU-E; 3661
Encyclopedic resources Wikidata; Q54971568
Experimental variables resources EFO; EFO_0022460
Entry history
Entry creation08-Jul-2015
Last entry update19-Dec-2024
Version number15