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Cellosaurus K#1 50K (CVCL_1H11)

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Cell line name K#1 50K
Synonyms K#1 50k; K #1 50K; CD8+ K#1 50K
Accession CVCL_1H11
Resource Identification Initiative To cite this cell line use: K#1 50K (RRID:CVCL_1H11)
Comments Characteristics: Has potent HIV-1-inhibitory activity.
Doubling time: 2 days (Patent=US6358511).
Transformant: NCBI_TaxID; 10381; Saimiriine herpesvirus 2 (Herpesvirus saimiri).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: T-cell; CL=CL_0000084.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Adult
Category Transformed cell line
Publications

Patent=US6358511
Mary Earley Klotman, Arevik Mosoian, Avelino Teixeira;
Inhibitors of HIV infection.
Patent number US6358511, 19-Mar-2002

PubMed=11752148; DOI=10.1128/JVI.76.2.569-581.2002; PMCID=PMC136805
Theresa Li-Yun Chang, Arevik Mosoian, Richard Pine, Mary Earley Klotman, John P. Moore;
A soluble factor(s) secreted from CD8(+) T lymphocytes inhibits human immunodeficiency virus type 1 replication through STAT1 activation.
J. Virol. 76:569-581(2002)

PubMed=16940531; DOI=10.1128/JVI.00589-06; PMCID=PMC1563913
Arevik Mosoian, Avelino Teixeira, Anthony A. High, Robert E. Christian, Donald Frederick Hunt, Jeffrey Shabanowitz, Xin-Yan Liu, Mary Earley Klotman;
Novel function of prothymosin alpha as a potent inhibitor of human immunodeficiency virus type 1 gene expression in primary macrophages.
J. Virol. 80:9200-9206(2006)

Cross-references
Encyclopedic resources Wikidata; Q54899230
Entry history
Entry creation08-Jul-2015
Last entry update29-Jun-2023
Version number7