Cellosaurus cell line K#1 50K (CVCL

Cross-references
Cell line name	K#1 50K
Synonyms	K#1 50k; K #1 50K; CD8+ K#1 50K
Accession	CVCL_1H11
Resource Identification Initiative	To cite this cell line use: K#1 50K (RRID:CVCL_1H11)
Comments	Characteristics: Has potent HIV-1-inhibitory activity. Doubling time: 2 days (Patent=US6358511). Transformant: NCBI_TaxID; 10381; Saimiriine herpesvirus 2 (Herpesvirus saimiri). Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178. Cell type: T-cell; CL=CL_0000084.
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Sex unspecified
Age at sampling	Adult
Category	Transformed cell line
Publications	Patent=US6358511 Klotman M.E., Mosoian A., Teixeira A. Inhibitors of HIV infection. Patent number US6358511, 19-Mar-2002 PubMed=11752148; DOI=10.1128/JVI.76.2.569-581.2002; PMCID=PMC136805 Chang T.L.-Y., Mosoian A., Pine R., Klotman M.E., Moore J.P. A soluble factor(s) secreted from CD8(+) T lymphocytes inhibits human immunodeficiency virus type 1 replication through STAT1 activation. J. Virol. 76:569-581(2002) PubMed=16940531; DOI=10.1128/JVI.00589-06; PMCID=PMC1563913 Mosoian A., Teixeira A., High A.A., Christian R.E., Hunt D.F., Shabanowitz J., Liu X.-Y., Klotman M.E. Novel function of prothymosin alpha as a potent inhibitor of human immunodeficiency virus type 1 gene expression in primary macrophages. J. Virol. 80:9200-9206(2006)
Encyclopedic resources	Wikidata; Q54899230
Entry history
Entry creation	08-Jul-2015
Last entry update	29-Jun-2023
Version number	7