Cellosaurus cell line PA086 (CVCL

Cellosaurus PA086 (CVCL_1G14)

Cross-references
Cell line name	PA086
Accession	CVCL_1G14
Resource Identification Initiative	To cite this cell line use: PA086 (RRID:CVCL_1G14)
Comments	Population: Japanese. Microsatellite instability: Stable (MSS) (PubMed=22156295). Omics: Genomics; Whole exome sequencing. Omics: Variations; SNP array analysis. Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations	Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Unspecified (PubMed=22156295). Mutation; HGNC; HGNC:11998; TP53; Simple; p.His193Tyr (c.577C>T); ClinVar=VCV000230256; Zygosity=Unspecified (PubMed=22156295).
Disease	Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Sex unspecified
Age at sampling	Age unspecified
Category	Cancer cell line
Publications	PubMed=22156295; DOI=10.1101/gr.123109.111; PMCID=PMC3266029 Ling-Hua Wang, Shuichi Tsutsumi, Tokuichi Kawaguchi, Koichi Nagasaki, Kenji Tatsuno, Shogo Yamamoto, Fei Sang, Kohtaro Sonoda, Minoru Sugawara, Akio Saiura, Seiko Hirono ...Show all 25 authors... , Hiroki Yamaue, Yoshio Miki, Minoru Isomura, Yasushi Totoki, Genta Nagae, Takayuki Isagawa, Hiroki Ueda, Satsuki Murayama-Hosokawa, Tatsuhiro Shibata, Hiromi Sakamoto, Yae Kanai, Atsushi Kaneda, Tetsuo Noda, Hiroyuki Aburatani; Show fewer authors Whole-exome sequencing of human pancreatic cancers and characterization of genomic instability caused by MLH1 haploinsufficiency and complete deficiency. Genome Res. 22:208-219(2012)
Cell line databases/resources	cancercelllines; CVCL_1G14
Encyclopedic resources	Wikidata; Q54937343
Polymorphism and mutation databases	Cosmic; 1820265
Entry history
Entry creation	08-Jul-2015
Last entry update	10-Apr-2025
Version number	13