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Cellosaurus HOS-CD4-CCR2b (CVCL_1D95)

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Cell line name HOS-CD4-CCR2b
Synonyms HOS-CD4-CCR-2B; HOS-CD4.CCR-2B; HOS.CD4.CCR2b
Accession CVCL_1D95
Resource Identification Initiative To cite this cell line use: HOS-CD4-CCR2b (RRID:CVCL_1D95)
Comments Population: Caucasian.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1603; CCR2 (Note=Isoform B).
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:1678; CD4.
Genetic integration: Method=Transfection; Gene=UniProtKB; P0A9M5; Escherichia coli gpt.
Derived from site: In situ; Bone, right femur; UBERON=UBERON_0000981.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg156Pro (c.467G>C); ClinVar=VCV000634768; Zygosity=Homozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_W650 (HOS-CD4)
Sex of cell Female
Age at sampling 13Y
Category Cancer cell line
Publications

PubMed=8649511; DOI=10.1038/381661a0
Hong-Kui Deng, Rong Liu, Wilfried Ellmeier, Sunny Choe, Derya Unutmaz, Michael Burkhart, Paola Di Marzio, Shoshana Marmon, Richard E. Sutton, C. Mark Hill, Craig B. Davis ...Show all 15 authors... , Stephen Chalmer Peiper, Thomas J. Schall, Dan Rudolf Littman, Nathaniel R. Landau; Show fewer authors
Identification of a major co-receptor for primary isolates of HIV-1.
Nature 381:661-666(1996)

Cross-references
Cell line collections (Providers) BEI_Resources; ARP-3315
Cell line databases/resources cancercelllines; CVCL_1D95
Encyclopedic resources Wikidata; Q54890165
Entry history
Entry creation08-Jul-2015
Last entry update14-Aug-2025
Version number16