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Cellosaurus U-CH11 (CVCL_1D67)

[Text version]
Cell line name U-CH11
Synonyms UCH11
Accession CVCL_1D67
Resource Identification Initiative To cite this cell line use: U-CH11 (RRID:CVCL_1D67)
Comments Population: Caucasian.
Doubling time: 10 days (PubMed=26183925); 15 days (Chordoma Foundation).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Bone, sacrum; UBERON=UBERON_0003690.
Sequence variations
Disease Sacral chordoma (NCIt: C129927)
Chordoma (ORDO: Orphanet_178)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_VR46 ! U-CH11R
Sex of cell Male
Age at sampling 71Y
Category Cancer cell line
STR profile Source(s): PubMed=26183925

Markers:
AmelogeninX
CSF1PO10,11
D3S135815
D7S8209,10
D8S117913,16
D13S31714
D16S5399,11
D18S5114
Penta D9,12
Penta E7,14
TH016,9.3
TPOX8

Run an STR similarity search on this cell line
Web pages Info; Chordoma Foundation; -; https://www.chordomafoundation.org/researchers/disease-models/u-ch11/
Publications

PubMed=26183925; DOI=10.1158/0008-5472.CAN-14-3270
Adrian von Witzleben, Lukas T. Goerttler, Ralf Marienfeld, Holger Barth, Andre Lechel, Kevin Mellert, Michael Bohm, Marko Kornmann, Regine Mayer-Steinacker, Alexandra von Baer, Markus Schultheiss ...Show all 15 authors... , Adrienne M. Flanagan, Peter Moller, Silke Bruderlein, Thomas F.E. Barth; Show fewer authors
Preclinical characterization of novel chordoma cell systems and their targeting by pharmocological inhibitors of the CDK4/6 cell-cycle pathway.
Cancer Res. 75:3823-3831(2015)

PubMed=28515451; DOI=10.1038/s41598-017-02174-5; PMCID=PMC5435709
Daniela Jager, Thomas F.E. Barth, Silke Bruderlein, Angelika Scheuerle, Beate Rinner, Adrian von Witzleben, Andre Lechel, Patrick Meyer, Regine Mayer-Steinacker, Alexandra von Baer, Markus Schultheiss ...Show all 14 authors... , Christian R. Wirtz, Peter Moller, Kevin Mellert; Show fewer authors
HOXA7, HOXA9, and HOXA10 are differentially expressed in clival and sacral chordomas.
Sci. Rep. 7:2032-2032(2017)

Cross-references
Cell line collections (Providers) ATCC; CRL-3302 - Discontinued
Cell line databases/resources cancercelllines; CVCL_1D67
Encyclopedic resources Wikidata; Q54973613
Gene expression databases GEO; GSM1673857
GEO; GSM1673858
Entry history
Entry creation08-Jul-2015
Last entry update10-Apr-2025
Version number17