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Cellosaurus MCF-7/164R-1 (CVCL_1D48)

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Cell line name MCF-7/164R-1
Synonyms MCF7/164R-1; 164R-1
Accession CVCL_1D48
Resource Identification Initiative To cite this cell line use: MCF-7/164R-1 (RRID:CVCL_1D48)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_31638; Fulvestrant (ICI 182780).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1D47 (MCF-7/S0.5)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
Publications

PubMed=7759159; DOI=10.1002/ijc.2910610417
Anne E. Lykkesfeldt, Soren S. Larsen, Per Briand;
Human breast cancer cell lines resistant to pure anti-estrogens are sensitive to tamoxifen treatment.
Int. J. Cancer 61:529-534(1995)

Cross-references
Cell line collections (Providers) CancerTools; 152091
Ximbio; 152091
Cell line databases/resources cancercelllines; CVCL_1D48
Encyclopedic resources Wikidata; Q54904338
Entry history
Entry creation08-Jul-2015
Last entry update19-Dec-2024
Version number17