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Cellosaurus BC-3C (CVCL_1958)

[Text version]
Cell line name BC-3C
Synonyms BC3c
Accession CVCL_1958
Resource Identification Initiative To cite this cell line use: BC-3C (RRID:CVCL_1958)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Caucasian.
Doubling time: ~25-30 hours (DSMZ=ACC-450).
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Genome ancestry Source: PubMed=30894373

Origin% genome
African1.78
Native American0.28
East Asian, North4.58
East Asian, South0
South Asian3.73
European, North37.13
European, South52.49
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 82Y
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-450

Markers:
AmelogeninX
CSF1PO11
D2S133817,25
D3S135817
D5S81811,13
D7S82011
D8S117914,15
D13S3179
D16S53911,13
D18S5114,21
D19S43314,15
D21S1129,32.2
FGA19,25
Penta D13,14
Penta E12,13
TH016,9
TPOX8
vWA15,16

Run an STR similarity search on this cell line
Publications

PubMed=9794224; DOI=10.1007/s11626-998-0068-z
Harris Pratsinis, Angelica Saetta, Sarantis Gagos, Panayiotis Davaris;
Isolation and characterization of a novel bladder cancer cell line: inhibition by epidermal growth factor.
In Vitro Cell. Dev. Biol. Anim. 34:722-728(1998)

PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027
Jordi Ginesta Barretina, Giordano Caponigro, Nicolas Stransky, Kavitha Venkatesan, Adam A. Margolin, Sungjoon Kim, Christopher J. Wilson, Joseph Lehar, Gregory V. Kryukov, Dmitriy Sonkin, Anupama Reddy ...Show all 61 authors... , Manway Liu, Lauren Murray, Michael F. Berger, John E. Monahan, Paula Morais, Jodi Meltzer, Adam Korejwa, Judit Jane-Valbuena, Felipa A. Mapa, Joseph Thibault, Eva Bric-Furlong, Pichai Raman, Aaron Shipway, Ingo H. Engels, Jill Cheng, Guo-Ying K. Yu, Jian-Jun Yu, Peter Aspesi Jr., Melanie de Silva, Kalpana Jagtap, Michael D. Jones, Li Wang, Charles Hatton, Emanuele Palescandolo, Supriya Gupta, Scott Mahan, Carrie Sougnez, Robert C. Onofrio, Ted Liefeld, Laura E. MacConaill, Wendy Winckler, Michael Reich, Nan-Xin Li, Jill P. Mesirov, Stacey B. Gabriel, Gad Getz, Kristin Ardlie, Vivien Chan, Vic E. Myer, Barbara L. Weber, Jeff Porter, Markus Warmuth, Peter Finan, Jennifer L. Harris, Matthew Langer Meyerson, Todd Robert Golub, Michael P. Morrissey, William Raj Sellers, Robert Schlegel, Levi Alexander Garraway; Show fewer authors
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=24367658; DOI=10.1371/journal.pone.0084411; PMCID=PMC3867501
Rebecca L. Ross, Julie E. Burns, Claire F. Taylor, Paul Mellor, Deborah H. Anderson, Margaret A. Knowles;
Identification of mutations in distinct regions of p85 alpha in urothelial cancer.
PLoS ONE 8:e84411.1-e84411.11(2013)

PubMed=24035680; DOI=10.1016/j.eururo.2013.08.057
Carolyn D. Hurst, Fiona M. Platt, Margaret A. Knowles;
Comprehensive mutation analysis of the TERT promoter in bladder cancer and detection of mutations in voided urine.
Eur. Urol. 65:367-369(2014)

PubMed=29732388; DOI=10.3233/BLC-180167; PMCID=PMC5929350
Tahlita C.M. Zuiverloon, Florus C. de Jong, James C. Costello, Dan Theodorescu;
Systematic review: characteristics and preclinical uses of bladder cancer cell lines.
Bladder Cancer 4:169-183(2018)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675
Julie Dutil, Zhi-Hua Chen, Alvaro N.A. Monteiro, Jamie K. Teer, Steven A. Eschrich;
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103
Mahmoud Ghandi, Franklin W. Huang, Judit Jane-Valbuena, Gregory V. Kryukov, Christopher C. Lo, E. Robert McDonald 3rd, Jordi Ginesta Barretina, Ellen T. Gelfand, Craig M. Bielski, Hao-Xin Li, Kevin Hu ...Show all 68 authors... , Alexander Y. Andreev-Drakhlin, Jaegil Kim, Julian M. Hess, Brian J. Haas, Francois Aguet, Barbara A. Weir, Michael V. Rothberg, Brenton R. Paolella, Michael Scott Lawrence, Rehan Akbani, Yi-Ling Lu, Hong L. Tiv, Prafulla C. Gokhale, Antoine de Weck, Ali Amin Mansour, Coyin Oh, Juliann Shih, Kevin Hadi, Yanay Rosen, Jonathan Bistline, Kavitha Venkatesan, Anupama Reddy, Dmitriy Sonkin, Manway Liu, Joseph Lehar, Joshua M. Korn, Dale A. Porter, Michael D. Jones, Javad Golji, Giordano Caponigro, Jordan E. Taylor, Caitlin M. Dunning, Amanda L. Creech, Allison C. Warren, James M. McFarland, Mahdi Zamanighomi, Audrey Kauffmann, Nicolas Stransky, Marcin Imielinski, Yosef E. Maruvka, Andrew D. Cherniack, Aviad Tsherniak, Francisca Vazquez, Jacob D. Jaffe, Andrew Alan Lane, David M. Weinstock, Cory M. Johannessen, Michael P. Morrissey, Frank Stegmeier, Robert Schlegel, William Chun Hahn, Gad Getz, Gordon B. Mills, Jesse S. Boehm, Todd Robert Golub, Levi Alexander Garraway, William Raj Sellers; Show fewer authors
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections (Providers) DSMZ; ACC-450
Cell line databases/resources CLO; CLO_0001893
cancercelllines; CVCL_1958
Cell_Model_Passport; SIDM01523
DepMap; ACH-000593
DSMZCellDive; ACC-450
Biological sample resources BioSample; SAMN03473550
BioSample; SAMN10988581
CRISP screens repositories BioGRID_ORCS_Cell_line; 506
Chemistry resources PharmacoDB; BC3C_80_2019
Encyclopedic resources Wikidata; Q54795193
Gene expression databases ArrayExpress; E-MTAB-2770
GEO; GSM886873
GEO; GSM887938
Polymorphism and mutation databases Cosmic; 1046690
Cosmic; 1285112
Cosmic; 1286004
Cosmic; 2050437
Cosmic; 2057442
Cosmic; 2444240
Cosmic; 2685938
IARC_TP53; 30018
LiGeA; CCLE_276
Progenetix; CVCL_1958
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number29