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Cellosaurus L-132 (CVCL_1908)

[Text version]
Cell line name L-132
Synonyms L132; L 132
Accession CVCL_1908
Resource Identification Initiative To cite this cell line use: L-132 (RRID:CVCL_1908)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=5641128; PubMed=566722; PubMed=1246601; PubMed=20143388). Originally thought to be a lung embryonic cell line.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00025.
Population: African American.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Omics: Genomics; Whole genome sequencing; Low read coverage.
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Children:
CVCL_M623 (L132 clone G-38-7)CVCL_5G52 (LC5)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
STR profile Source(s): ATCC=CCL-5; ECACC=89111004; KCLB=10005

Markers:
AmelogeninX
CSF1PO9,10
D2S133817
D3S135815,18
D5S81811,12
D7S8208,12
D8S117912,13
D13S31712,13.3 (ATCC=CCL-5; KCLB=10005)
12,14 (ECACC=89111004)
D16S5399,10
D18S5116
D19S43313,14
D21S1127,28
FGA18,21
Penta D8,15
Penta E7,17
TH017
TPOX8,12
vWA16,18

Run an STR similarity search on this cell line
Web pages Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

CLPUB00071
Davis E.V., Bolin V.S.
Continuous cultivation of isogenous cell lines from the human embryo.
Fed. Proc. 19:386.15-386.15(1960)

PubMed=14185313; DOI=10.1126/science.146.3641.241
Cell Culture Collection Committee
Animal cell strains. The Cell Culture Collection Committee has assembled and certified 23 strains of animal cells.
Science 146:241-243(1964)

PubMed=5641128; DOI=10.1038/217750a0
Gartler S.M.
Apparent Hela cell contamination of human heteroploid cell lines.
Nature 217:750-751(1968)

DOI=10.1007/BF02618370
Stulberg C.S., Coriell L.L., Kniazeff A.J., Shannon J.E.
The animal cell culture collection.
In Vitro 5:1-16(1970)

PubMed=1246601; DOI=10.1126/science.1246601
Nelson-Rees W.A., Flandermeyer R.R.
HeLa cultures defined.
Science 191:96-98(1976)

PubMed=566722; DOI=10.1007/BF02616110
Lavappa K.S.
Survey of ATCC stocks of human cell lines for HeLa contamination.
In Vitro 14:469-475(1978)

DOI=10.2198/sbk.34.289
Mizusawa H.
Operation of the JCRB cell bank and isoenzyme.
Seibutsu Butsuri Kagaku 34:289-292(1990)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

PubMed=23925245; DOI=10.1038/nature12064; PMCID=PMC3740412
Adey A.C., Burton J.N., Kitzman J.O., Hiatt J.B., Lewis A.P., Martin B.K., Qiu R.-L., Lee C., Shendure J.
The haplotype-resolved genome and epigenome of the aneuploid HeLa cancer cell line.
Nature 500:207-211(2013)

Cross-references
Cell line collections (Providers) ATCC; CCL-5
BCRJ; 0139
ECACC; 89111004
IZSLER; BS CL 55
JCRB; NIHS0050 - Discontinued
KCLB; 10005
Cell line databases/resources CLO; CLO_0007140
CLO; CLO_0007158
CLO; CLO_0007159
CLDB; cl3076
CLDB; cl3077
CLDB; cl3078
Biological sample resources BioSample; SAMN03151735
Chemistry resources ChEMBL-Cells; CHEMBL3307504
ChEMBL-Targets; CHEMBL613999
PubChem_Cell_line; CVCL_1908
Encyclopedic resources Wikidata; Q54900860
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number29