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Cellosaurus Intestine 407 (CVCL_1907)

[Text version]
Cell line name Intestine 407
Synonyms intestine 407; Intestine-407; intestine-407; INT 407; Int 407; INT-407; Int-407; Int407; INT407; INT 407(HeLa derivative); HI407; Henle-407; 407; HEI
Accession CVCL_1907
Resource Identification Initiative To cite this cell line use: Intestine 407 (RRID:CVCL_1907)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=4864103; PubMed=5641128; PubMed=566722; PubMed=1246601; PubMed=20143388). Originally thought to originate from embryonic intestinal cells (jejunum/ileum).
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00008.
Population: African American.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Omics: Genome sequenced (low read coverage).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
STR profile Source(s): ATCC=CCL-6; PubMed=11416159

Penta D8,15
Penta E7,17

Run an STR similarity search on this cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx

PubMed=13431913; DOI=10.3181/00379727-94-23044
Foley G.E., Handler A.H.
Differentiation of normal and neoplastic cells maintained in tissue culture by implantation into normal hamsters.
Proc. Soc. Exp. Biol. Med. 94:661-664(1957)

PubMed=13475808; DOI=10.4049/jimmunol.79.1.54
Henle G., Deinhardt F.W.
The establishment of strains of human cells in tissue culture.
J. Immunol. 79:54-59(1957)

PubMed=14185313; DOI=10.1126/science.146.3641.241
Cell Culture Collection Committee
Animal cell strains. The Cell Culture Collection Committee has assembled and certified 23 strains of animal cells.
Science 146:241-243(1964)

Gartler S.M.
Genetic markers as tracers in cell culture.
Natl. Cancer Inst. Monogr. 26:167-195(1967)

PubMed=5641128; DOI=10.1038/217750a0
Gartler S.M.
Apparent Hela cell contamination of human heteroploid cell lines.
Nature 217:750-751(1968)

Stulberg C.S., Coriell L.L., Kniazeff A.J., Shannon J.E.
The animal cell culture collection.
In Vitro 5:1-16(1970)

PubMed=1246601; DOI=10.1126/science.1246601
Nelson-Rees W.A., Flandermeyer R.R.
HeLa cultures defined.
Science 191:96-98(1976)

PubMed=566722; DOI=10.1007/BF02616110
Lavappa K.S.
Survey of ATCC stocks of human cell lines for HeLa contamination.
In Vitro 14:469-475(1978)

PubMed=11416159; DOI=10.1073/pnas.121616198
Masters J.R.W., Thomson J.A., Daly-Burns B., Reid Y.A., Dirks W.G., Packer P., Toji L.H., Ohno T., Tanabe H., Arlett C.F., Kelland L.R., Harrison M., Virmani A.K., Ward T.H., Ayres K.L., Debenham P.G.
Short tandem repeat profiling provides an international reference standard for human cell lines.
Proc. Natl. Acad. Sci. U.S.A. 98:8012-8017(2001)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

PubMed=23925245; DOI=10.1038/nature12064
Adey A.C., Burton J.N., Kitzman J.O., Hiatt J.B., Lewis A.P., Martin B.K., Qiu R.-L., Lee C., Shendure J.
The haplotype-resolved genome and epigenome of the aneuploid HeLa cancer cell line.
Nature 500:207-211(2013)

PubMed=34697958; DOI=10.1177/24725552211051963
Korch C.T., Capes-Davis A.
The extensive and expensive impacts of HEp-2 [HeLa], intestine 407 [HeLa], and other false cell lines in journal publications.
SLAS Discov. 26:1268-1279(2021)

Cell line collections (Providers) ATCC; CCL-6
BCRC; 60022 - Discontinued
ECACC; 85051004
RCB; RCB0553 - Discontinued
Cell line databases/resources CLO; CLO_0006953
CLO; CLO_0006954
CLO; CLO_0006955
CLDB; cl2895
CLDB; cl2896
CLDB; cl2897
CLDB; cl2898
Anatomy/cell type resources BTO; BTO:0000633
Biological sample resources BioSample; SAMN03151723
Encyclopedic resources Wikidata; Q54897826
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number32