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Cellosaurus U-2940 (CVCL_1897)

[Text version]
Cell line name U-2940
Synonyms U2940
Accession CVCL_1897
Resource Identification Initiative To cite this cell line use: U-2940 (RRID:CVCL_1897)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: LL-100 blood cancer cell line panel.
Part of: MD Anderson Cell Lines Project.
Characteristics: Genetically heterogeneous, consists of 2 subclones (PubMed=27566572).
Doubling time: ~50 hours (DSMZ=ACC-634).
Omics: Deep exome analysis.
Omics: Protein expression by reverse-phase protein arrays.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Donor information: Originally the patient was suffering from Hodgkin lymphoma.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
HLA typing Source: DSMZCellDive=ACC-634
Class I
HLA-AA*02:01:01,02:01:01
HLA-BB*07:02:01,07:02:01
HLA-CC*07:02:01,07:02:01
Class II
HLA-DPDPA1*02:06,02:06
HLA-DQDQA1*01:02:01,01:02:01
DQB1*06:02:01,06:02:01
HLA-DRDRA*01:02:03,01:02:03
DRB1*15:01:01,15:01:01
Disease Diffuse large B-cell lymphoma (NCIt: C8851)
Diffuse large B-cell lymphoma (ORDO: Orphanet_544)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 18Y
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-634

Markers:
AmelogeninX
CSF1PO12
D2S133819
D3S135816,17
D5S81811,12
D7S82010,12
D8S117912
D13S3178,10
D16S53910,12
D18S5112,17
D19S43314,15
D21S1129
FGA24,26
Penta D14,15
Penta E7,14
TH017,9.3
TPOX8,12
vWA17

Run an STR similarity search on this cell line
Web pages https://tcpaportal.org/mclp/
Publications

PubMed=16106419; DOI=10.1002/ijc.21417
Sambade C., Berglund M., Lagercrantz S., Sallstrom J., Reis R.M., Enblad G., Glimelius B., Sundstrom C.
U-2940, a human B-cell line derived from a diffuse large cell lymphoma sequential to Hodgkin lymphoma.
Int. J. Cancer 118:555-563(2006)

PubMed=27566572; DOI=10.18632/oncotarget.11524; PMCID=PMC5325377
Quentmeier H., Pommerenke C., Ammerpohl O., Geffers R., Hauer V., MacLeod R.A.F., Nagel S., Romani J., Rosati E., Rosen A., Uphoff C.C., Zaborski M., Drexler H.G.
Subclones in B-lymphoma cell lines: isogenic models for the study of gene regulation.
Oncotarget 7:63456-63465(2016)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076
Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P., Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

PubMed=29533902; DOI=10.1515/hsz-2017-0321
Drexler H.G., Pommerenke C., Eberth S., Nagel S.
Hodgkin lymphoma cell lines: to separate the wheat from the chaff.
Biol. Chem. 399:511-523(2018)

PubMed=31160637; DOI=10.1038/s41598-019-44491-x; PMCID=PMC6547646
Quentmeier H., Pommerenke C., Dirks W.G., Eberth S., Koeppel M., MacLeod R.A.F., Nagel S., Steube K.G., Uphoff C.C., Drexler H.G.
The LL-100 panel: 100 cell lines for blood cancer studies.
Sci. Rep. 9:8218-8218(2019)

Cross-references
Cell line collections (Providers) DSMZ; ACC-634
Cell line databases/resources cancercelllines; CVCL_1897
DepMap; ACH-001678
DSMZCellDive; ACC-634
Lonza; 1539
Biological sample resources BioSample; SAMN03473453
Chemistry resources ChEMBL-Cells; CHEMBL4523523
ChEMBL-Targets; CHEMBL4523554
PubChem_Cell_line; CVCL_1897
Encyclopedic resources Wikidata; Q54973561
Gene expression databases ArrayExpress; E-MTAB-7721
ArrayExpress; E-MTAB-7722
GEO; GSM1374972
GEO; GSM1897963
Polymorphism and mutation databases Cosmic; 2437272
Cosmic; 2479246
Progenetix; CVCL_1897
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number25