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Cellosaurus NCEB-1 (CVCL_1875)

[Text version]
Cell line name NCEB-1
Synonyms Nceb-1; NCEB1; NCEB
Accession CVCL_1875
Resource Identification Initiative To cite this cell line use: NCEB-1 (RRID:CVCL_1875)
Comments Part of: Lymphoma Research Foundation Mantle Cell Lymphoma cell bank (LRF MCL cell bank).
Part of: MD Anderson Cell Lines Project.
Doubling time: 72-96 hours (PubMed=2848599); 19 hours (PubMed=25315077); ~50-70 hours (DSMZ=ACC-721).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Omics: Proteomics; Expression; Reverse-phase protein array.
Omics: Transcriptomics; Microarray.
Omics: Variations; Array-based CGH.
Omics: Variations; SNP array analysis.
Caution: Established from a 57 year old male patient but contains some intact murine chromosomes (ATCC; PubMed=16448697) so should be considered as an hybrid cell line.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
Disease Mantle cell lymphoma (NCIt: C4337)
Mantle cell lymphoma (ORDO: Orphanet_52416)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Category Hybrid cell line
STR profile Source(s): ATCC=CRL-3005; DSMZ=ACC-721

Markers:

Run an STR similarity search on this cell line
Web pages Info; MCLP; -; https://tcpaportal.org/mclp/
Publications

PubMed=2848599; DOI=10.1182/blood.V72.6.2026.2026
David L. Saltman, Philip G. Cachia, Agnes Edna Dewar, Fiona M. Ross, Andrew S. Krajewski, Christopher Armstrong Ludlam, Christopher Michael Steel;
Characterization of a new non-Hodgkin's lymphoma cell line (NCEB-1) with a chromosomal (11:14) translocation [t(11:14)(q13;q32)].
Blood 72:2026-2030(1988)

PubMed=7849311; DOI=10.1182/blood.V85.4.893.bloodjournal854893
Gail Stranks, Susan E. Height, Paul Mitchell, Dalal Mouneimne Jadayel, Martin A.R. Yuille, Corinne F.M. De Lord, Robyn D. Clutterbuck, Jennie G. Treleaven, Ray Leonard Powles, Elisabeth Nacheva, David G. Oscier ...Show all 17 authors... , Abraham Karpas, Gilbert Marcel Lenoir, Stephen D. Smith, John L. Millar, Daniel Catovsky, Martin John Swinnerton Dyer; Show fewer authors
Deletions and rearrangement of CDKN2 in lymphoid malignancy.
Blood 85:893-901(1995)

DOI=10.1016/B978-0-12-221970-2.50457-5
Hans Gunther Drexler;
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

PubMed=12169673; DOI=10.1016/S1525-1578(10)60693-9; PMCID=PMC1906980
Ryan S. Robetorye, Sandra Dawn Bohling, John W. Morgan, G. Chris Fillmore, Megan S. Lim, Kojo Seys John Elenitoba-Johnson;
Microarray analysis of B-cell lymphoma cell lines with the t(14;18).
J. Mol. Diagn. 4:123-136(2002)

PubMed=16183118; DOI=10.1016/j.leukres.2005.08.016
Catherine A. Tucker, Gwyn Bebb, Richard J. Klasa, Mukesh Chhanabhai, Valia S. Lestou, Douglas E. Horsman, Randy D. Gascoyne, Adrian Wiestner, Dana Masin, Marcel Bally, Michael E. Williams;
Four human t(11;14)(q13;q32)-containing cell lines having classic and variant features of mantle cell lymphoma.
Leuk. Res. 30:449-457(2006)

PubMed=16448697; DOI=10.1016/j.leukres.2005.11.013
Jordi Camps, Itziar Salaverria, Maria J. Garcia, Esther Prat, Silvia Bea, Jessica C.M. Pole, Lluis Hernandez, Javier Del Rey, Juan Cruz Cigudosa, Marta Bernues, Carlos Caldas ...Show all 14 authors... , Dolors Colomer, Rosa Miro, Elias Campo; Show fewer authors
Genomic imbalances and patterns of karyotypic variability in mantle-cell lymphoma cell lines.
Leuk. Res. 30:923-934(2006)

PubMed=16960149; DOI=10.1182/blood-2006-06-026500
Cinta Mestre-Escorihuela, Fanny Rubio-Moscardo, Jose A. Richter, Reiner Siebert, Joan Climent, Vicente Fresquet, Elena Beltran, Xabier Agirre, Isabel Marugan, Miguel Marin, Andreas Rosenwald ...Show all 21 authors... , Kei-ji Sugimoto, Luise M. Wheat, E. Loraine Karran, Juan Fernando Garcia Garcia, Lydia Sanchez-Verde, Felipe Prosper, Louis Michael Staudt, Daniel Pinkel, Martin John Swinnerton Dyer, Jose Angel Martinez-Climent; Show fewer authors
Homozygous deletions localize novel tumor suppressor genes in B-cell lymphomas.
Blood 109:271-280(2007)

PubMed=25315077; DOI=10.3109/10428194.2014.970548
Laura K. Fogli, Michael E. Williams, Joseph M. Connors, Yvonne A. Reid, Kathleen Brown, Owen A. O'Connor;
Development and characterization of a Mantle Cell Lymphoma Cell Bank in the American Type Culture Collection.
Leuk. Lymphoma 56:2114-2122(2015)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076
Jun Li, Wei Zhao, Rehan Akbani, Wen-Bin Liu, Zhen-Lin Ju, Shi-Yun Ling, Christopher P. Vellano, Paul Roebuck, Qing-Hua Yu, A. Karina Eterovic, Lauren Averett Byers ...Show all 25 authors... , Michael A. Davies, Wan-Leng Deng, Y.N. Vashisht Gopal, Guo Chen, Erika Maria von Euw, Dennis Joseph Slamon, Dylan Conklin, John Victor Heymach, Adi F. Gazdar, John D. Minna, Jeffrey N. Myers, Yi-Ling Lu, Gordon B. Mills, Han Liang; Show fewer authors
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

Cross-references
Cell line collections (Providers) ATCC; CRL-3005
DSMZ; ACC-721
Cell line databases/resources cancercelllines; CVCL_1875
DSMZCellDive; ACC-721
Biological sample resources BioSample; SAMN03471708
Encyclopedic resources Wikidata; Q54907697
Gene expression databases GEO; GSM95564
GEO; GSM95569
GEO; GSM104461
GEO; GSM115803
Polymorphism and mutation databases Cosmic; 1070711
Cosmic; 2296994
IARC_TP53; 25019
Progenetix; CVCL_1875
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number27