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Cellosaurus Tanoue (CVCL_1852)

[Text version]
Cell line name Tanoue
Synonyms TANOUE
Accession CVCL_1852
Resource Identification Initiative To cite this cell line use: Tanoue (RRID:CVCL_1852)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: MD Anderson Cell Lines Project.
Population: Japanese.
Doubling time: ~48 hours (PubMed=7538617); ~40 hours (DSMZ=ACC-399).
Omics: Protein expression by reverse-phase protein arrays.
Omics: Deep quantitative proteome analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Met246Thr (c.737T>C); ClinVar=VCV000428886; Zygosity=Heterozygous (PubMed=15901131; DepMap=ACH-001669).
Disease Childhood B acute lymphoblastic leukemia (NCIt: C9140)
Precursor B-cell acute lymphoblastic leukemia (ORDO: Orphanet_99860)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_U347 (ST [Human leukemia])
Sex of cell Male
Age at sampling 11Y
Category Cancer cell line
STR profile Source(s): DepMap=ACH-001669; DSMZ=ACC-399; RCB=RCB1180

D5S81810,11,12 (DepMap=ACH-001669; RCB=RCB1180)
11,12 (DSMZ=ACC-399)
D16S53910,12,13,14 (DepMap=ACH-001669)
12,13 (DSMZ=ACC-399; RCB=RCB1180)
FGA19,22,23 (DepMap=ACH-001669)
14,22,23 (DSMZ=ACC-399)
Penta D11,13
Penta E14,18,19
vWA14,18,19 (DepMap=ACH-001669; RCB=RCB1180)
14,19 (DSMZ=ACC-399)

Run an STR similarity search on this cell line
Web pages https://tcpaportal.org/mclp/

PubMed=7538617; DOI=10.1016/0145-2126(94)00156-5
El-Sonbaty S.S., Tsuchiya H., Watanabe M., Hochito K., Kunisada T., Shimosaka A., Matsuda I.
Exogenous expression of human granulocyte colony-stimulating factor receptor in a B-lineage acute lymphoblastic leukemia cell line: a possible model for mixed lineage leukemia.
Leuk. Res. 19:249-256(1995)

Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

PubMed=15843827; DOI=10.1038/sj.leu.2403749
Andersson A., Eden P., Lindgren D., Nilsson J., Lassen C., Heldrup J., Fontes M., Borg A., Mitelman F., Johansson B., Hoglund M., Fioretos T.
Gene expression profiling of leukemic cell lines reveals conserved molecular signatures among subtypes with specific genetic aberrations.
Leukemia 19:1042-1050(2005)

PubMed=15901131; DOI=10.1016/j.prp.2005.01.002
Murai Y., Hayashi S., Takahashi H., Tsuneyama K., Takano Y.
Correlation between DNA alterations and p53 and p16 protein expression in cancer cell lines.
Pathol. Res. Pract. 201:109-115(2005)

PubMed=16408098; DOI=10.1038/sj.leu.2404081
Quentmeier H., MacLeod R.A.F., Zaborski M., Drexler H.G.
JAK2 V617F tyrosine kinase mutation in cell lines derived from myeloproliferative disorders.
Leukemia 20:471-476(2006)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=24590883; DOI=10.1002/gcc.22161
Murga Penas E.-M., Schilling G., Behrmann P., Klokow M., Vettorazzi E., Bokemeyer C., Dierlamm J.
Comprehensive cytogenetic and molecular cytogenetic analysis of 44 Burkitt lymphoma cell lines: secondary chromosomal changes characterization, karyotypic evolution, and comparison with primary samples.
Genes Chromosomes Cancer 53:497-515(2014)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P., Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

PubMed=35354797; DOI=10.1038/s41467-022-29224-5
Leo I.R., Aswad L., Stahl M., Kunold E., Post F., Erkers T., Struyf N., Mermelekas G., Joshi R.N., Gracia-Villacampa E., Ostling P., Kallioniemi O.-P., Pokrovskaja Tamm K., Siavelis I., Lehtio J., Vesterlund M., Jafari R.
Integrative multi-omics and drug response profiling of childhood acute lymphoblastic leukemia cell lines.
Nat. Commun. 13:1691.1-1691.19(2022)

Cell line collections (Providers) DSMZ; ACC-399
RCB; RCB1180
Cell line databases/resources CLO; CLO_0009269
CLO; CLO_0050979
cancercelllines; CVCL_1852
Cell_Model_Passport; SIDM00288
DepMap; ACH-001669
DSMZCellDive; ACC-399
Biological sample resources BioSample; SAMN03472169
BioSample; SAMN03473578
CRISP screens repositories BioGRID_ORCS_Cell_line; 1759
Encyclopedic resources Wikidata; Q54971725
Experimental variables resources EFO; EFO_0002380
Gene expression databases ArrayExpress; E-MTAB-38
GEO; GSM5137747
Polymorphism and mutation databases Cosmic; 1012122
Cosmic; 1130258
Cosmic; 1281385
IARC_TP53; 21631
Progenetix; CVCL_1852
Proteomic databases PRIDE; PXD023662
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number31