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Cellosaurus PaCaDD-135 (CVCL_1849)

[Text version]
Cell line name PaCaDD-135
Synonyms PACADD-135; PACADD135
Accession CVCL_1849
Resource Identification Initiative To cite this cell line use: PaCaDD-135 (RRID:CVCL_1849)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Caucasian.
Doubling time: 43.83 hours (PubMed=21683373); ~72 hours (DSMZ=ACC-710).
Omics: Deep exome analysis.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000027.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Unspecified (PubMed=21683373; DepMap=ACH-001376).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg249fs (c.746_750_delGGCCC); Zygosity=Unspecified (DepMap=ACH-001376).
Disease Pancreatic adenocarcinoma (NCIt: C8294)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 48Y
Category Cancer cell line
STR profile Source(s): DepMap=ACH-001376; DSMZ=ACC-710

Markers:
AmelogeninX
CSF1PO10
D2S133818,20
D3S135815,16
D5S81811,12
D7S82011,12
D8S117913
D13S31711,13
D16S53911,12
D18S5117
D19S43313,15
D21S1129
FGA19
Penta D2,12 (DSMZ=ACC-710)
12 (DepMap=ACH-001376)
Penta E5,11
TH019,9.3
TPOX8,11
vWA14,19

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Publications

PubMed=21683373; DOI=10.1016/j.jss.2011.04.021
Ruckert F., Aust D., Bohme I., Werner K., Brandt A., Diamandis E.P., Krautz C., Hering S., Saeger H.-D., Grutzmann R., Pilarsky C.
Five primary human pancreatic adenocarcinoma cell lines established by the outgrowth method.
J. Surg. Res. 172:29-39(2012)

DOI=10.4172/2324-9293.1000104
Wagenhauser M.U., Ruckert F., Niedergethmann M., Grutzmann R., Saeger H.-D.
Distribution of characteristic mutations in native ductal adenocarcinoma of the pancreas and pancreatic cancer cell lines.
Cell Biol. Res. Ther. 2:1000104.1-1000104.5(2013)

Cross-references
Cell line collections (Providers) DSMZ; ACC-710
Cell line databases/resources cancercelllines; CVCL_1849
Cell_Model_Passport; SIDM01353
DepMap; ACH-001376
DSMZCellDive; ACC-710
Encyclopedic resources Wikidata; Q54937422
Polymorphism and mutation databases Cosmic; 1559064
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number22