• Gene deletion; HGNC; HGNC:6770; SMAD4; Zygosity=Homozygous (PubMed=10408907).
  
• Mutation; HGNC; HGNC:3373; EP300; Unexplicit; Ex17-19del (c.4342del448); Zygosity=Homozygous (PubMed=10700188).
  
• Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (Cosmic-CLP=1240201; DepMap=ACH-000023).
  
• Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg282Trp (c.844C>T); ClinVar=VCV000012364; Zygosity=Homozygous (PubMed=10700188; Cosmic-CLP=1240201; DepMap=ACH-000023).
  

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PubMed=22585861; DOI=10.1158/2159-8290.CD-11-0224; PMCID=PMC5057396
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PubMed=25167228; DOI=10.1038/bjc.2014.475; PMCID=PMC4453732
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KRAS mutational subtype and copy number predict in vitro response of human pancreatic cancer cell lines to MEK inhibition.
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PubMed=25485619; DOI=10.1038/nbt.3080
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PubMed=25877200; DOI=10.1038/nature14397
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PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076
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PubMed=29444439; DOI=10.1016/j.celrep.2018.01.051; PMCID=PMC6343826
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PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675
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PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103
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Nature 569:503-508(2019)

PubMed=31978347; DOI=10.1016/j.cell.2019.12.023; PMCID=PMC7339254
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PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775
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