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Cellosaurus MAVER-1 (CVCL_1831)

[Text version]
Cell line name MAVER-1
Synonyms Maver-1; MAVER1; Maver1; MAVER; MAntle cell VERona-1
Accession CVCL_1831
Resource Identification Initiative To cite this cell line use: MAVER-1 (RRID:CVCL_1831)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: Lymphoma Research Foundation Mantle Cell Lymphoma cell bank (LRF MCL cell bank).
Doubling time: 24 hours (PubMed=25315077); ~48 hours (DSMZ=ACC-717).
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
HLA typing Source: PubMed=25960936
Class I
HLA-AA*68:01,02:01
HLA-BB*55:01,07:02
HLA-CC*03:03,07:02
Class II
HLA-DQDQA1*05:01,02:01
DQB1*03:01,02:01
HLA-DRDRB1*11:01,07:01

Source: PubMed=25688540
Class I
HLA-AA*24,26
HLA-BB*38,44
HLA-CC*05,12
Disease Mantle cell lymphoma (NCIt: C4337)
Mantle cell lymphoma (ORDO: Orphanet_52416)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 82Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-3008; DSMZ=ACC-717

Markers:
AmelogeninX,Y
CSF1PO10,11
D2S133817
D3S135817
D5S81812
D7S8208
D8S117911
D13S3178,13
D16S5399,12
D18S5116
D19S43316
D21S1129,33.2
FGA19,21
Penta D10,11
Penta E5,12
TH018,9
TPOX8,12
vWA14,18

Run an STR similarity search on this cell line
Publications

PubMed=16434369
Alberto Zamo, German Ott, Tiemo Katzenberger, Patrick Adam, Claudia Parolini, Aldo Scarpa, Maurizio Lestani, Fabio Menestrina, Marco Chilosi;
Establishment of the MAVER-1 cell line, a model for leukemic and aggressive mantle cell lymphoma.
Haematologica 91:40-47(2006)

PubMed=24362935; DOI=10.1038/nm.3435
Rami Rahal, Mareike Frick, Rodrigo Romero, Joshua M. Korn, Robert Kridel, Fong Chun Chan, Barbara Meissner, Hyo-eun Carrie Bhang, David A. Ruddy, Audrey Kauffmann, Ali Farsidjani ...Show all 30 authors... , Adnan Derti, Daniel Rakiec, Tara Naylor, Estelle Pfister, Steve Kovats, Sunkyu Kim, Kerstin Dietze, Bernd Dorken, Christian Steidl, Alexandar Tzankov, Michael Hummel, John E. Monahan, Michael P. Morrissey, Christine Fritsch, William Raj Sellers, Vesselina G. Cooke, Randy D. Gascoyne, Georg Lenz, Frank Stegmeier; Show fewer authors
Pharmacological and genomic profiling identifies NF-kappaB-targeted treatment strategies for mantle cell lymphoma.
Nat. Med. 20:87-92(2014)

PubMed=25960936; DOI=10.4161/21624011.2014.954893; PMCID=PMC4355981
Sebastian Boegel, Martin Lower, Thomas Bukur, Ugur Sahin, John C. Castle;
A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines.
OncoImmunology 3:e954893.1-e954893.12(2014)

PubMed=25315077; DOI=10.3109/10428194.2014.970548
Laura K. Fogli, Michael E. Williams, Joseph M. Connors, Yvonne A. Reid, Kathleen Brown, Owen A. O'Connor;
Development and characterization of a Mantle Cell Lymphoma Cell Bank in the American Type Culture Collection.
Leuk. Lymphoma 56:2114-2122(2015)

PubMed=25688540; DOI=10.1002/cyto.a.22643
Sophie Maiga, Carole Brosseau, Geraldine Descamps, Christelle Dousset, Patricia Gomez-Bougie, David Chiron, Emmanuelle Menoret, Charlotte Kervoelen, Henri Vie, Anne Cesbron, Agnes Moreau-Aubry ...Show all 13 authors... , Martine Amiot, Catherine Pellat-Deceunynck; Show fewer authors
A simple flow cytometry-based barcode for routine authentication of multiple myeloma and mantle cell lymphoma cell lines.
Cytometry A 87:285-288(2015)

PubMed=27697772; DOI=10.1182/blood-2016-06-720490
David Chiron, Celine Bellanger, Antonin Papin, Benoit Tessoulin, Christelle Dousset, Sophie Maiga, Anne Moreau, Julie Esbelin, Valerie Trichet, Selina Chen-Kiang, Philippe Moreau ...Show all 15 authors... , Cyrille Touzeau, Steven Le Gouill, Martine Amiot, Catherine Pellat-Deceunynck; Show fewer authors
Rational targeted therapies to overcome microenvironment-dependent expansion of mantle cell lymphoma.
Blood 128:2808-2818(2016)

PubMed=29666304; DOI=10.1158/1078-0432.CCR-17-3004
Lan V. Pham, Sheng-Jian Huang, Hui Zhang, Jun Zhang, Taylor Bell, Shou-Hao Zhou, Elizabeth Pogue, Zhi-Yong Ding, Laura Lam, Jason Westin, R. Eric Davis ...Show all 17 authors... , Ken H. Young, L. Jeffrey Medeiros, Richard Joseph Ford Jr., Krystle Nomie, Leo Zhang, Michael Wang; Show fewer authors
Strategic therapeutic targeting to overcome venetoclax resistance in aggressive B-cell lymphomas.
Clin. Cancer Res. 24:3967-3980(2018)

Cross-references
Cell line collections (Providers) ATCC; CRL-3008
DSMZ; ACC-717
Cell line databases/resources cancercelllines; CVCL_1831
DepMap; ACH-002485
DSMZCellDive; ACC-717
Biological sample resources BioSample; SAMN03471709
Chemistry resources ChEMBL-Cells; CHEMBL4482995
ChEMBL-Targets; CHEMBL4483260
PubChem_Cell_line; CVCL_1831
Encyclopedic resources Wikidata; Q54904067
Gene expression databases GEO; GSM1044978
GEO; GSM1044979
GEO; GSM1044980
GEO; GSM1044981
GEO; GSM1266781
GEO; GSM1266782
GEO; GSM1266793
GEO; GSM1266794
GEO; GSM1266795
GEO; GSM1266796
GEO; GSM1266797
GEO; GSM1266798
GEO; GSM2322621
Polymorphism and mutation databases Cosmic; 2078182
Cosmic; 2088018
IARC_TP53; 24552
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number28