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Cellosaurus CRO-AP3 (CVCL_1810)

[Text version]
Cell line name CRO-AP3
Synonyms CRO-AP/3; CROAP3; AP3
Accession CVCL_1810
Resource Identification Initiative To cite this cell line use: CRO-AP3 (RRID:CVCL_1810)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: COSMIC cell lines project.
Population: Caucasian.
Virology: Contains 10 to 30 copies of the human herpesvirus 8 (HHV-8/KSHV) genome per cell.
Doubling time: ~50 hours (DSMZ=ACC-275).
Transformant: NCBI_TaxID; 37296; Human herpesvirus 8 (HHV-8/KSHV).
Omics: Genomics; Whole exome sequencing.
Omics: Phenotyping; Drug screening.
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Genome ancestry Source: PubMed=30894373

Origin% genome
African2.63
Native American0
East Asian, North0.61
East Asian, South1.52
South Asian1.46
European, North42.74
European, South51.05
Disease Primary effusion lymphoma (NCIt: C6915)
Primary effusion lymphoma (ORDO: Orphanet_48686)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 42Y
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-275

Markers:
AmelogeninX
CSF1PO11
D2S133821,24
D3S135814
D5S81813
D7S82010,12
D8S117915
D13S31711,12
D16S5399,13
D18S5112,16
D19S43314,16
D21S1130.2,32.2
FGA21,26
Penta D9,13
Penta E12,14
TH018
TPOX8
vWA16,18

Run an STR similarity search on this cell line
Web pages Info; COPE; -; http://www.cells-talk.com/index.php/page/copelibrary?key=CRO-AP%2f3
Publications

PubMed=9734661; DOI=10.1046/j.1365-2141.1998.00877.x
Antonino Carbone, Anna M. Cilia, Annunziata Gloghini, Daniela Capello, Michela Todesco, Silvia Quattrone, Rachele Volpe, Gianluca Gaidano;
Establishment and characterization of EBV-positive and EBV-negative primary effusion lymphoma cell lines harbouring human herpesvirus type-8.
Br. J. Haematol. 102:1081-1089(1998)

PubMed=9766492; DOI=10.1038/sj.leu.2401160
Hans Gunther Drexler, Cord C. Uphoff, Gianluca Gaidano, Antonino Carbone;
Lymphoma cell lines: in vitro models for the study of HHV-8+ primary effusion lymphomas (body cavity-based lymphomas).
Leukemia 12:1507-1517(1998)

PubMed=10784388; DOI=10.3109/10428190009148391
Antonino Carbone, Anna M. Cilia, Annunziata Gloghini, Daniela Capello, Tiziana Perin, Daniela Bontempo, Vincenzo Canzonieri, Umberto Tirelli, Rachele Volpe, Gianluca Gaidano;
Primary effusion lymphoma cell lines harbouring human herpesvirus type-8.
Leuk. Lymphoma 36:447-456(2000)

DOI=10.1016/B978-0-12-221970-2.50457-5
Hans Gunther Drexler;
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675
Julie Dutil, Zhi-Hua Chen, Alvaro N.A. Monteiro, Jamie K. Teer, Steven A. Eschrich;
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line collections (Providers) DSMZ; ACC-275
Cell line databases/resources CLO; CLO_0002618
cancercelllines; CVCL_1810
Cell_Model_Passport; SIDM00070
Cosmic-CLP; 1297440
DepMap; ACH-002393
DSMZCellDive; ACC-275
Anatomy/cell type resources BTO; BTO_0002725
Biological sample resources BioSample; SAMN03473339
Chemistry resources GDSC; 1297440
PharmacoDB; CROAP3_265_2019
Encyclopedic resources Wikidata; Q54814507
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number32