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Cellosaurus TE-1 (CVCL_1759)

[Text version]

Cell line name TE-1
Synonyms TE1
Accession CVCL_1759
Resource Identification Initiative To cite this cell line use: TE-1 (RRID:CVCL_1759)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: COSMIC cell lines project.
Population: Japanese.
Doubling time: 60 hours (PubMed=520749).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: Deep quantitative proteome analysis.
Omics: Deep RNAseq analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Esophagus.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Val272Met (c.814G>A); ClinVar=VCV000185814; Zygosity=Unspecified (PubMed=9096669).
Genome ancestry Source: PubMed=30894373

Origin% genome
African0.32
Native American0
East Asian, North85.61
East Asian, South11.65
South Asian0
European, North0
European, South2.41
Disease Esophageal squamous cell carcinoma (NCIt: C4024)
Squamous cell carcinoma of the esophagus (ORDO: Orphanet_99977)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_C3M0 (TE-1R)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
STR profile Source(s): CCRID; Cosmic-CLP; RCB; TKG

Markers:
AmelogeninX
CSF1PO10,12
D2S133819,20
D3S135816
D5S81811
D7S82011 (TKG)
10,11 (CCRID; Cosmic-CLP; RCB)
D8S117911,13
D13S31710
D16S53912
D18S5117
D19S43314,15.2
D21S1128
FGA24
TH017
TPOX8,11 (Cosmic-CLP; RCB; TKG)
11 (CCRID)
vWA17,18

Run an STR similarity search on this cell line
Publications

PubMed=520749; DOI=10.20772/cancersci1959.70.5_575
Nishihira T., Kasai M., Mori S., Watanabe T., Kuriya Y., Suda M., Kitamura M., Hirayama K., Akaishi T., Sasaki T.
Characteristics of two cell lines (TE-1 and TE-2) derived from human squamous cell carcinoma of the esophagus.
Gann 70:575-584(1979)

PubMed=2990217
Yee C., Krishnan-Hewlett I., Baker C.C., Schlegel R., Howley P.M.
Presence and expression of human papillomavirus sequences in human cervical carcinoma cell lines.
Am. J. Pathol. 119:361-366(1985)

PubMed=2420787; DOI=10.1016/S0021-9258(17)38506-X
Banks-Schlegel S.P., Quintero J.
Human esophageal carcinoma cells have fewer, but higher affinity epidermal growth factor receptors.
J. Biol. Chem. 261:4359-4362(1986)

PubMed=3518877; DOI=10.3109/07357908609038260
Fogh J.
Human tumor lines for cancer research.
Cancer Invest. 4:157-184(1986)

PubMed=2302677; DOI=10.1016/0165-4608(90)90073-j
Whang-Peng J., Banks-Schlegel S.P., Lee E.C.
Cytogenetic studies of esophageal carcinoma cell lines.
Cancer Genet. Cytogenet. 45:101-120(1990)

PubMed=1778766; DOI=10.1111/j.1349-7006.1991.tb01816.x
Takeshima E., Hamaguchi M., Watanabe T., Akiyama S., Kataoka M., Ohnishi Y., Xiao H.Y., Nagai Y., Takagi H.
Aberrant elevation of tyrosine-specific phosphorylation in human gastric cancer cells.
Jpn. J. Cancer Res. 82:1428-1435(1991)

PubMed=8509434; DOI=10.1007/BF01215923
Nishihira T., Hashimoto Y., Katayama M., Mori S., Kuroki T.
Molecular and cellular features of esophageal cancer cells.
J. Cancer Res. Clin. Oncol. 119:441-449(1993)

PubMed=9096669; DOI=10.1002/(SICI)1097-0215(19970328)71:1<79::AID-IJC14>3.0.CO;2-4
Barnas C., Martel-Planche G., Furukawa Y., Hollstein M., Montesano R., Hainaut P.
Inactivation of the p53 protein in cell lines derived from human esophageal cancers.
Int. J. Cancer 71:79-87(1997)

PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D
Jia L.-Q., Osada M., Ishioka C., Gamo M., Ikawa S., Suzuki T., Shimodaira H., Niitani T., Kudo T., Akiyama M., Kimura N., Matsuo M., Mizusawa H., Tanaka N., Koyama H., Namba M., Kanamaru R., Kuroki T.
Screening the p53 status of human cell lines using a yeast functional assay.
Mol. Carcinog. 19:243-253(1997)

PubMed=15172977; DOI=10.1158/0008-5472.CAN-04-0172
Sonoda I., Imoto I., Inoue J., Shibata T., Shimada Y., Chin K., Imamura M., Amagasa T., Gray J.W., Hirohashi S., Inazawa J.
Frequent silencing of low density lipoprotein receptor-related protein 1B (LRP1B) expression by genetic and epigenetic mechanisms in esophageal squamous cell carcinoma.
Cancer Res. 64:3741-3747(2004)

PubMed=17804709; DOI=10.1158/0008-5472.CAN-07-2064
Boonstra J.J., van der Velden A.W., Beerens E.C., van Marion R., Morita-Fujimura Y., Matsui Y., Nishihira T., Tselepis C., Hainaut P., Lowe A.W., Beverloo H.B., van Dekken H., Tilanus H.W., Dinjens W.N.M.
Mistaken identity of widely used esophageal adenocarcinoma cell line TE-7.
Cancer Res. 67:7996-8001(2007)

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.-Y.K., Yu J.-J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N.-X., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

DOI=10.1155/2014/376541
Akagi I., Ishibashi O., Matsutani T., Hagiwara N., Matsuda A., Nomura T., Makino H., Yoshida H., Miyashita M., Uchida E.
Comprehensive analysis of microRNA and mRNA expression in normal and tumorous human esophageal squamous cell lines using microarray datasets.
Dataset Papers Sci. 2013:376541.1-376541.3(2013)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X.-M., Egan R.K., Liu Q.-S., Mironenko T., Mitropoulos X., Richardson L., Wang J.-H., Zhang T.-H., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=28224081; DOI=10.1016/j.gdata.2017.02.002
Akagi I., Ishibashi O.
RNA-Seq analysis of human cell lines established from normal and neoplastic esophageal squamous epithelium.
Genomics Data 12:4-6(2017)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J.G., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

PubMed=31978347; DOI=10.1016/j.cell.2019.12.023
Nusinow D.P., Szpyt J., Ghandi M., Rose C.M., McDonald E.R. III, Kalocsay M., Jane-Valbuena J., Gelfand E.T., Schweppe D.K., Jedrychowski M.P., Golji J., Porter D.A., Rejtar T., Wang Y.K., Kryukov G.V., Stegmeier F., Erickson B.K., Garraway L.A., Sellers W.R., Gygi S.P.
Quantitative proteomics of the Cancer Cell Line Encyclopedia.
Cell 180:387-402.e16(2020)

PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010
Goncalves E., Poulos R.C., Cai Z.-X., Barthorpe S., Manda S.S., Lucas N., Beck A., Bucio-Noble D., Dausmann M., Hall C., Hecker M., Koh J., Lightfoot H., Mahboob S., Mali I., Morris J., Richardson L., Seneviratne A.J., Shepherd R., Sykes E., Thomas F., Valentini S., Williams S.G., Wu Y.-X., Xavier D., MacKenzie K.L., Hains P.G., Tully B., Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.
Pan-cancer proteomic map of 949 human cell lines.
Cancer Cell 40:835-849.e8(2022)

PubMed=36090890; DOI=10.1155/2022/5632744
Gu Z.-L., Zhu W.-G., Wang W.-W., Xu Y.-Y., Jiang L., Huang J.-S., Huang J.
Anlotinib inhibits tumor angiogenesis and promotes the anticancer effect of radiotherapy on esophageal cancer through inhibiting EphA2.
J. Oncol. 2022:5632744.1-5632744.11(2022)

Cross-references
Cell line collections BCRJ; 0371
CLS; 305060
KCB; KCB 200737YJ
RCB; RCB1894
TKG; TKG 0252
Cell line databases/resources CLO; CLO_0051369
CCRID; 3101HUMTCHu89
Cell_Model_Passport; SIDM00369
CGH-DB; 305-1
CGH-DB; 9254-4
Cosmic-CLP; 753621
DepMap; ACH-000647
LINCS_LDP; LCL-1564
Anatomy/cell type resources BTO; BTO:0004601
Biological sample resources BioSample; SAMN03472084
BioSample; SAMN10988294
Chemistry resources ChEMBL-Cells; CHEMBL3308178
ChEMBL-Targets; CHEMBL2366092
GDSC; 753621
PharmacoDB; TE1_1575_2019
PubChem_Cell_line; CVCL_1759
Encyclopedic resources Wikidata; Q54972007
Gene expression databases ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-2770
ArrayExpress; E-MTAB-3610
GEO; GSM301571
GEO; GSM887695
GEO; GSM888788
GEO; GSM1508955
GEO; GSM1508959
GEO; GSM1670528
Polymorphism and mutation databases Cosmic; 730296
Cosmic; 735780
Cosmic; 753621
Cosmic; 801322
Cosmic; 923173
Cosmic; 926097
Cosmic; 983713
Cosmic; 1043226
Cosmic; 1123318
Cosmic; 1612896
Cosmic; 2650636
Cosmic; 2698418
IARC_TP53; 6329
LiGeA; CCLE_791
Progenetix; CVCL_1759
Proteomic databases PRIDE; PXD030304
Sequence databases EGA; EGAS00001000978
Entry history
Entry creation04-Apr-2012
Last entry update15-Dec-2022
Version number37