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Cellosaurus TE-1 (CVCL_1759)

[Text version]
Cell line name TE-1
Synonyms TE1
Accession CVCL_1759
Resource Identification Initiative To cite this cell line use: TE-1 (RRID:CVCL_1759)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: COSMIC cell lines project.
Population: Japanese.
Doubling time: 60 hours (PubMed=520749).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Genomics; DNA methylation analysis.
Omics: Genomics; Whole exome sequencing.
Omics: Phenotyping; Drug screening.
Omics: Proteomics; Quantitative.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Omics: Variations; Array-based CGH.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Esophagus; UBERON=UBERON_0001043.
Sequence variations
HLA typing Source: PubMed=26589293
Class I
HLA-AA*24:02,26:01
HLA-BB*35:01,39:01
HLA-CC*03:03,07:02
Genome ancestry Source: PubMed=30894373

Origin% genome
African0.32
Native American0
East Asian, North85.61
East Asian, South11.65
South Asian0
European, North0
European, South2.41
Disease Esophageal squamous cell carcinoma (NCIt: C4024)
Squamous cell carcinoma of the esophagus (ORDO: Orphanet_99977)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_E1MX (HyCyte TE-1 KO-hCHST1)CVCL_C3M0 (TE-1R)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
STR profile Source(s): CCRID=3101HUMTCHu89; Cosmic-CLP=753621; RCB=RCB1894; TKG=TKG 0252

Markers:
AmelogeninX
CSF1PO10,12
D2S133819,20
D3S135816
D5S81811
D7S82010,11 (CCRID=3101HUMTCHu89; Cosmic-CLP=753621; RCB=RCB1894)
11 (TKG=TKG 0252)
D8S117911,13
D13S31710
D16S53912
D18S5117
D19S43314,15.2
D21S1128
FGA24
TH017
TPOX8,11 (Cosmic-CLP=753621; RCB=RCB1894; TKG=TKG 0252)
11 (CCRID=3101HUMTCHu89)
vWA17,18

Run an STR similarity search on this cell line
Publications

PubMed=520749; DOI=10.20772/cancersci1959.70.5_575
Tetsuro Nishihira, Morio Kasai, Shozo Mori, Toshio Watanabe, Yoshiki Kuriya, Makoto Suda, Michihiko Kitamura, Katsu Hirayama, Takashi Akaishi, Takashi Sasaki;
Characteristics of two cell lines (TE-1 and TE-2) derived from human squamous cell carcinoma of the esophagus.
Gann 70:575-584(1979)

PubMed=2990217; PMCID=PMC1888002
Carole Yee, Indira Krishnan-Hewlett, Carl C. Baker, Richard Schlegel, Peter Maxwell Howley;
Presence and expression of human papillomavirus sequences in human cervical carcinoma cell lines.
Am. J. Pathol. 119:361-366(1985)

PubMed=2420787; DOI=10.1016/S0021-9258(17)38506-X
Susan P. Banks-Schlegel, Jesse Quintero;
Human esophageal carcinoma cells have fewer, but higher affinity epidermal growth factor receptors.
J. Biol. Chem. 261:4359-4362(1986)

PubMed=3518877; DOI=10.3109/07357908609038260
Jorgen Fogh;
Human tumor lines for cancer research.
Cancer Invest. 4:157-184(1986)

PubMed=2302677; DOI=10.1016/0165-4608(90)90073-j
Jacqueline Whang-Peng, Susan P. Banks-Schlegel, Elaine C. Lee;
Cytogenetic studies of esophageal carcinoma cell lines.
Cancer Genet. Cytogenet. 45:101-120(1990)

PubMed=1778766; DOI=10.1111/j.1349-7006.1991.tb01816.x; PMCID=PMC5918361
Eisuke Takeshima, Michinari Hamaguchi, Tadashi Watanabe, Seiji Akiyama, Masato Kataoka, Yukano Ohnishi, Heng-Yi Xiao, Yoshiyuki Nagai, Hiroshi Takagi;
Aberrant elevation of tyrosine-specific phosphorylation in human gastric cancer cells.
Jpn. J. Cancer Res. 82:1428-1435(1991)

PubMed=8509434; DOI=10.1007/BF01215923
Tetsuro Nishihira, Yu Hashimoto, Masafumi Katayama, Shozo Mori, Toshio Kuroki;
Molecular and cellular features of esophageal cancer cells.
J. Cancer Res. Clin. Oncol. 119:441-449(1993)

PubMed=9096669; DOI=10.1002/(SICI)1097-0215(19970328)71:1<79::AID-IJC14>3.0.CO;2-4
Christoph Barnas, Ghyslaine Martel-Planche, Yoichi Furukawa, Monica C. Hollstein, Ruggero Montesano, Pierre Hainaut;
Inactivation of the p53 protein in cell lines derived from human esophageal cancers.
Int. J. Cancer 71:79-87(1997)

PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D
Li-Qun Jia, Motonobu Osada, Chikashi Ishioka, Makio Gamo, Shuntaro Ikawa, Takao Suzuki, Hideki Shimodaira, Tomohito Niitani, Toshio Kudo, Mitoshi Akiyama, Narimiti Kimura ...Show all 18 authors... , Mitsuyoshi Matsuo, Hiroshi Mizusawa, Noriho Tanaka, Hideki Koyama, Masayoshi Namba, Ryunosuke Kanamaru, Toshio Kuroki; Show fewer authors
Screening the p53 status of human cell lines using a yeast functional assay.
Mol. Carcinog. 19:243-253(1997)

PubMed=15172977; DOI=10.1158/0008-5472.CAN-04-0172
Itaru Sonoda, Issei Imoto, Jun Inoue, Tatsuhiro Shibata, Yutaka Shimada, Koei Chin, Masayuki Imamura, Teruo Amagasa, Joe W. Gray, Setsuo Hirohashi, Johji Inazawa;
Frequent silencing of low density lipoprotein receptor-related protein 1B (LRP1B) expression by genetic and epigenetic mechanisms in esophageal squamous cell carcinoma.
Cancer Res. 64:3741-3747(2004)

PubMed=17804709; DOI=10.1158/0008-5472.CAN-07-2064
Jurjen J. Boonstra, Albertina W. van der Velden, Erwin C.W. Beerens, Ronald van Marion, Yuiko Morita-Fujimura, Yasuhisa Matsui, Tetsuro Nishihira, Chris Tselepis, Pierre Hainaut, Anson W. Lowe, H. Berna Beverloo ...Show all 14 authors... , Herman van Dekken, Hugo W. Tilanus, Winand N.M. Dinjens; Show fewer authors
Mistaken identity of widely used esophageal adenocarcinoma cell line TE-7.
Cancer Res. 67:7996-8001(2007)

PubMed=18973137; DOI=10.1002/gcc.20626
Takashi Sugimoto, Naohiko Seki, Satoya Shimizu, Naoko Kikkawa, Jun Tsukada, Hideaki Shimada, Keita Sasaki, Toyoyuki Hanazawa, Yoshitaka Okamoto, Akira Hata;
The galanin signaling cascade is a candidate pathway regulating oncogenesis in human squamous cell carcinoma.
Genes Chromosomes Cancer 48:132-142(2009)

PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113
Graham Robert Bignell, Christopher D. Greenman, Helen R. Davies, Adam P. Butler, Sarah Edkins, Jenny M. Andrews, Gemma Buck, Lina Chen, David Beare, Calli Latimer, Sara Widaa ...Show all 22 authors... , Jonathan Hinton, Ciara Fahey, Bei-Yuan Fu, Sajani Swamy, Gillian L. Dalgliesh, Bin Tean Teh, Panos Deloukas, Feng-Tang Yang, Peter J. Campbell, P. Andrew Futreal, Michael Rudolf Stratton; Show fewer authors
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027
Jordi Ginesta Barretina, Giordano Caponigro, Nicolas Stransky, Kavitha Venkatesan, Adam A. Margolin, Sungjoon Kim, Christopher J. Wilson, Joseph Lehar, Gregory V. Kryukov, Dmitriy Sonkin, Anupama Reddy ...Show all 61 authors... , Manway Liu, Lauren Murray, Michael F. Berger, John E. Monahan, Paula Morais, Jodi Meltzer, Adam Korejwa, Judit Jane-Valbuena, Felipa A. Mapa, Joseph Thibault, Eva Bric-Furlong, Pichai Raman, Aaron Shipway, Ingo H. Engels, Jill Cheng, Guo-Ying K. Yu, Jian-Jun Yu, Peter Aspesi Jr., Melanie de Silva, Kalpana Jagtap, Michael D. Jones, Li Wang, Charles Hatton, Emanuele Palescandolo, Supriya Gupta, Scott Mahan, Carrie Sougnez, Robert C. Onofrio, Ted Liefeld, Laura E. MacConaill, Wendy Winckler, Michael Reich, Nan-Xin Li, Jill P. Mesirov, Stacey B. Gabriel, Gad Getz, Kristin Ardlie, Vivien Chan, Vic E. Myer, Barbara L. Weber, Jeff Porter, Markus Warmuth, Peter Finan, Jennifer L. Harris, Matthew Langer Meyerson, Todd Robert Golub, Michael P. Morrissey, William Raj Sellers, Robert Schlegel, Levi Alexander Garraway; Show fewer authors
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

DOI=10.1155/2014/376541
Ichiro Akagi, Osamu Ishibashi, Takeshi Matsutani, Nobutoshi Hagiwara, Akihisa Matsuda, Tsutomu Nomura, Hiroshi Makino, Hiroshi Yoshida, Masao Miyashita, Eiji Uchida;
Comprehensive analysis of microRNA and mRNA expression in normal and tumorous human esophageal squamous cell lines using microarray datasets.
Dataset Papers Sci. 2013:376541.1-376541.3(2013)

PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878
Jelle Scholtalbers, Sebastian Boegel, Thomas Bukur, Marius Byl, Sebastian Goerges, Patrick Sorn, Martin Loewer, Ugur Sahin, John C. Castle;
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Genome Med. 7:118.1-118.7(2015)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469
Francesco Iorio, Theo A. Knijnenburg, Daniel J. Vis, Graham Robert Bignell, Michael Patrick Menden, Michael Schubert, Nanne Aben, Emanuel Goncalves, Syd Barthorpe, Howard Lightfoot, Thomas Cokelaer ...Show all 39 authors... , Patricia Greninger, Ewald van Dyk, Han Chang, Heshani de Silva, Holger Heyn, Xian-Ming Deng, Regina K. Egan, Qing-Song Liu, Tatiana Mironenko, Xeni Mitropoulos, Laura Richardson, Jin-Hua Wang, Ting-Hu Zhang, Sebastian Moran, Sergi Sayols, Maryam Soleimani, David Tamborero, Nuria Lopez-Bigas, Petra Ross-Macdonald, Manel Esteller, Nathanael S. Gray, Daniel Arie Haber, Michael Rudolf Stratton, Cyril Henri Benes, Lodewyk F.A. Wessels, Julio Saez-Rodriguez, Ultan McDermott, Mathew J. Garnett; Show fewer authors
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=28224081; DOI=10.1016/j.gdata.2017.02.002; PMCID=PMC5304241
Ichiro Akagi, Osamu Ishibashi;
RNA-Seq analysis of human cell lines established from normal and neoplastic esophageal squamous epithelium.
Genom. Data 12:4-6(2017)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675
Julie Dutil, Zhi-Hua Chen, Alvaro N.A. Monteiro, Jamie K. Teer, Steven A. Eschrich;
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103
Mahmoud Ghandi, Franklin W. Huang, Judit Jane-Valbuena, Gregory V. Kryukov, Christopher C. Lo, E. Robert McDonald 3rd, Jordi Ginesta Barretina, Ellen T. Gelfand, Craig M. Bielski, Hao-Xin Li, Kevin Hu ...Show all 68 authors... , Alexander Y. Andreev-Drakhlin, Jaegil Kim, Julian M. Hess, Brian J. Haas, Francois Aguet, Barbara A. Weir, Michael V. Rothberg, Brenton R. Paolella, Michael Scott Lawrence, Rehan Akbani, Yi-Ling Lu, Hong L. Tiv, Prafulla C. Gokhale, Antoine de Weck, Ali Amin Mansour, Coyin Oh, Juliann Shih, Kevin Hadi, Yanay Rosen, Jonathan Bistline, Kavitha Venkatesan, Anupama Reddy, Dmitriy Sonkin, Manway Liu, Joseph Lehar, Joshua M. Korn, Dale A. Porter, Michael D. Jones, Javad Golji, Giordano Caponigro, Jordan E. Taylor, Caitlin M. Dunning, Amanda L. Creech, Allison C. Warren, James M. McFarland, Mahdi Zamanighomi, Audrey Kauffmann, Nicolas Stransky, Marcin Imielinski, Yosef E. Maruvka, Andrew D. Cherniack, Aviad Tsherniak, Francisca Vazquez, Jacob D. Jaffe, Andrew Alan Lane, David M. Weinstock, Cory M. Johannessen, Michael P. Morrissey, Frank Stegmeier, Robert Schlegel, William Chun Hahn, Gad Getz, Gordon B. Mills, Jesse S. Boehm, Todd Robert Golub, Levi Alexander Garraway, William Raj Sellers; Show fewer authors
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

PubMed=31978347; DOI=10.1016/j.cell.2019.12.023; PMCID=PMC7339254
David Paul Nusinow, John Szpyt, Mahmoud Ghandi, Christopher M. Rose, E. Robert McDonald 3rd, Marian Kalocsay, Judit Jane-Valbuena, Ellen T. Gelfand, Devin K. Schweppe, Mark P. Jedrychowski, Javad Golji ...Show all 20 authors... , Dale A. Porter, Tomas Rejtar, Y. Karen Wang, Gregory V. Kryukov, Frank Stegmeier, Brian K. Erickson, Levi Alexander Garraway, William Raj Sellers, Steven P. Gygi; Show fewer authors
Quantitative proteomics of the Cancer Cell Line Encyclopedia.
Cell 180:387-402.e16(2020)

PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775
Emanuel Goncalves, Rebecca C. Poulos, Zhao-Xiang Cai, Syd Barthorpe, Srikanth S. Manda, Natasha Lucas, Alexandra Beck, Daniel Bucio-Noble, Michael Dausmann, Caitlin Hall, Michael Hecker ...Show all 32 authors... , Jennifer Koh, Howard Lightfoot, Sadia Mahboob, Iman Mali, James Morris, Laura Richardson, Akila J. Seneviratne, Rebecca Shepherd, Erin Sykes, Frances Thomas, Sara Valentini, Steven G. Williams, Yang-Xiu Wu, Dylan Xavier, Karen L. MacKenzie, Peter G. Hains, Brett Tully, Phillip James Robinson, Qing Zhong, Mathew J. Garnett, Roger Robert Reddel; Show fewer authors
Pan-cancer proteomic map of 949 human cell lines.
Cancer Cell 40:835-849.e8(2022)

PubMed=36090890; DOI=10.1155/2022/5632744; PMCID=PMC9452983
Zhen-Lin Gu, Wei-Guo Zhu, Wan-Wei Wang, Ying-Ying Xu, Lei Jiang, Jia-Sheng Huang, Jing Huang;
Anlotinib inhibits tumor angiogenesis and promotes the anticancer effect of radiotherapy on esophageal cancer through inhibiting EphA2.
J. Oncol. 2022:5632744.1-5632744.11(2022)

Cross-references
Cell line collections (Providers) ABM; T9161
BCRJ; 0371
CLS; 305060
KCB; KCB 200737YJ
RCB; RCB1894
TKG; TKG 0252
Cell line databases/resources CLO; CLO_0051369
cancercelllines; CVCL_1759
CCRID; 3101HUMTCHu89
Cell_Model_Passport; SIDM00369
CGH-DB; 305-1
CGH-DB; 9254-4
Cosmic-CLP; 753621
DepMap; ACH-000647
LINCS_LDP; LCL-1564
Anatomy/cell type resources BTO; BTO_0004601
Biological sample resources BioSample; SAMN03472084
BioSample; SAMN10988294
CRISP screens repositories BioGRID_ORCS_Cell_line; 356
Chemistry resources ChEMBL-Cells; CHEMBL3308178
ChEMBL-Targets; CHEMBL2366092
GDSC; 753621
PharmacoDB; TE1_1575_2019
PubChem_Cell_line; CVCL_1759
Encyclopedic resources Wikidata; Q54972007
Experimental variables resources EFO; EFO_0022658
Gene expression databases ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-2770
ArrayExpress; E-MTAB-3610
GEO; GSM301571
GEO; GSM887695
GEO; GSM888788
GEO; GSM1508955
GEO; GSM1508959
GEO; GSM1670528
Polymorphism and mutation databases Cosmic; 730296
Cosmic; 735780
Cosmic; 753621
Cosmic; 801322
Cosmic; 923173
Cosmic; 926097
Cosmic; 983713
Cosmic; 1043226
Cosmic; 1123318
Cosmic; 1612896
Cosmic; 2650636
Cosmic; 2698418
IARC_TP53; 6329
LiGeA; CCLE_791
Progenetix; CVCL_1759
Proteomic databases PRIDE; PXD030304
Sequence databases EGA; EGAS00001000978
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number45