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Cellosaurus TE 381.T (CVCL_1751)

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Cell line name TE 381.T
Synonyms TE-381-T; TE381T; RD114-B
Accession CVCL_1751
Resource Identification Initiative To cite this cell line use: TE 381.T (RRID:CVCL_1751)
Comments Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Population: Caucasian.
Characteristics: Established through passage of the parent cell line in a fetal cat (ATCC=CRL-7763).
Omics: Variations; SNP array analysis.
Caution: Wrongly indicated by ATCC to originate from a 7 week old female donor. Older product sheets of ATCC correctly indicated it originates from a 7 year old female.
Derived from site: In situ; Pelvis, muscle; UBERON=UBERON_0001325.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61His (c.183A>T); ClinVar=VCV000373003; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Trp (c.742C>T); ClinVar=VCV000012347; Zygosity=Homozygous (from parent cell line).
Disease Embryonal rhabdomyosarcoma (NCIt: C8971)
Embryonal rhabdomyosarcoma (ORDO: Orphanet_99757)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1649 (RD)
Sex of cell Female
Age at sampling 7Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-7763

Markers:
AmelogeninX
CSF1PO10,11
D2S133817,23
D3S135815,17
D5S81811
D7S8208,12
D8S117911,15
D13S31713
D16S53910,11
D18S5113,18
D19S43311
D21S1128,29
FGA20,21
Penta D11,13
Penta E12
TH019.3
TPOX9
vWA18

Run an STR similarity search on this cell line
Publications

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662
S. Michael Rothenberg, Gayatry Mohapatra, Miguel N. Rivera, Daniel Winokur, Patricia Greninger, Mai Nitta, Peter M. Sadow, Gaya Sooriyakumar, Brian W. Brannigan, Matthew J. Ulman, Rushika M. Perera ...Show all 22 authors... , Rui Wang, Angela Tam, Xiao-Jun Ma, Mark Erlander, Dennis C. Sgroi, James W. Rocco, Mark W. Lingen, Ezra E.W. Cohen, David Neil Louis, Jeffrey Settleman, Daniel Arie Haber; Show fewer authors
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

Cross-references
Cell line collections (Providers) ATCC; CRL-7763
Cell line databases/resources CLO; CLO_0009300
cancercelllines; CVCL_1751
IGRhCellID; TE381T
Encyclopedic resources Wikidata; Q54971966
Gene expression databases ArrayExpress; E-MTAB-38
Polymorphism and mutation databases Cosmic; 1309332
Progenetix; CVCL_1751
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number18