Cellosaurus RPMI-6666 (CVCL_1665)
Cell line name | RPMI-6666 | ||||||||||||||||||
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Synonyms | RPMI 6666; RPMI6666; Roswell Park Memorial Institute 6666 | ||||||||||||||||||
Accession | CVCL_1665 | ||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: RPMI-6666 (RRID:CVCL_1665) | ||||||||||||||||||
Comments | Problematic cell line: Misclassified. Originally thought to be a Hodgkin lymphoma cell line but is a B-lymphoblastoid cell line (PubMed=12592342; PubMed=20143388; PubMed=29533902). Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). Part of: COSMIC cell lines project. Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00263. Microsatellite instability: Stable (MSS) (Sanger). Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV). Omics: Deep exome analysis. Omics: Deep quantitative proteome analysis. Omics: DNA methylation analysis. Omics: SNP array analysis. Omics: Transcriptome analysis by microarray. | ||||||||||||||||||
HLA typing | Source: PubMed=12133989
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Genome ancestry | Source: PubMed=30894373
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Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||
Sex of cell | Male | ||||||||||||||||||
Age at sampling | 29Y | ||||||||||||||||||
Category | Transformed cell line | ||||||||||||||||||
STR profile | Source(s): ATCC; Cosmic-CLP; ECACC Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||
Web pages | https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx | ||||||||||||||||||
Publications | PubMed=12133989; DOI=10.4049/jimmunol.169.3.1593 PubMed=12592342; DOI=10.1038/sj.leu.2402799 PubMed=20143388; DOI=10.1002/ijc.25242 PubMed=20164919; DOI=10.1038/nature08768 PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458 PubMed=22460905; DOI=10.1038/nature11003 PubMed=27397505; DOI=10.1016/j.cell.2016.06.017 PubMed=29533902; DOI=10.1515/hsz-2017-0321 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747 PubMed=31068700; DOI=10.1038/s41586-019-1186-3 PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010 | ||||||||||||||||||
Cross-references | |||||||||||||||||||
Cell line collections | ATCC; CCL-113
ECACC; 87081807 KCLB; 10113 | ||||||||||||||||||
Cell line databases/resources | CLO; CLO_0008870
Cell_Model_Passport; SIDM00813 Cosmic-CLP; 909701 DepMap; ACH-001182 IGRhCellID; RPMI6666 LINCS_LDP; LCL-2013 | ||||||||||||||||||
Biological sample resources | BioSample; SAMN03151630
BioSample; SAMN03472694 BioSample; SAMN10988187 | ||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3308884
ChEMBL-Targets; CHEMBL2366187 GDSC; 909701 PharmacoDB; RPMI6666_1325_2019 PubChem_Cell_line; CVCL_1665 | ||||||||||||||||||
Encyclopedic resources | Wikidata; Q54951196 | ||||||||||||||||||
Experimental variables resources | EFO; EFO_0002321 | ||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-38
ArrayExpress; E-MTAB-783 ArrayExpress; E-MTAB-3610 GEO; GSM887546 GEO; GSM888629 GEO; GSM1670387 | ||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 684228
Cosmic; 909701 IARC_TP53; 21291 | ||||||||||||||||||
Proteomic databases | PRIDE; PXD030304 | ||||||||||||||||||
Sequence databases | EGA; EGAS00001000978 | ||||||||||||||||||
Entry history | |||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||
Last entry update | 21-Mar-2023 | ||||||||||||||||||
Version number | 32 |