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Cellosaurus RF-48 (CVCL_1657)

[Text version]
Cell line name RF-48
Synonyms RF48
Accession CVCL_1657
Resource Identification Initiative To cite this cell line use: RF-48 (RRID:CVCL_1657)
Comments Problematic cell line: Misclassified. From a B-cell lymphoma and not from the ascites of a gastric adenocarcinoma (PubMed=12226758).
Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: COSMIC cell lines project.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: Deep quantitative proteome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Genome ancestry Source: PubMed=30894373

Origin% genome
Native American31.68
East Asian, North3.25
East Asian, South0
South Asian2.87
European, North27.68
European, South29.24
Disease Lymphoma (NCIt: C3208)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_3580 ! RF-1
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-1863; Cosmic-CLP=909697


Run an STR similarity search on this cell line

PubMed=7750094; DOI=10.1016/0304-3835(95)03717-b
Salesiotis A.N., Wang C.K., Wang C.D., Burger A., Li H., Seth A.
Identification of novel genes from stomach cancer cell lines by differential display.
Cancer Lett. 91:47-54(1995)

PubMed=12226758; DOI=10.1038/sj.onc.1205829
Ji J.-F., Chen X., Leung S.Y., Chi J.-T.A., Chu K.M., Yuen S.T., Li R., Chan A.S.Y., Li J.-Y., Dunphy N., So S.
Comprehensive analysis of the gene expression profiles in human gastric cancer cell lines.
Oncogene 21:6549-6556(2002)

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X.-M., Egan R.K., Liu Q.-S., Mironenko T., Mitropoulos X., Richardson L., Wang J.-H., Zhang T.-H., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010
Goncalves E., Poulos R.C., Cai Z.-X., Barthorpe S., Manda S.S., Lucas N., Beck A., Bucio-Noble D., Dausmann M., Hall C., Hecker M., Koh J., Lightfoot H., Mahboob S., Mali I., Morris J., Richardson L., Seneviratne A.J., Shepherd R., Sykes E., Thomas F., Valentini S., Williams S.G., Wu Y.-X., Xavier D., MacKenzie K.L., Hains P.G., Tully B., Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.
Pan-cancer proteomic map of 949 human cell lines.
Cancer Cell 40:835-849.e8(2022)

Cell line collections (Providers) ATCC; CRL-1863 - Discontinued
Cell line databases/resources CLO; CLO_0037147
cancercelllines; CVCL_1657
Cell_Model_Passport; SIDM01092
Cosmic-CLP; 909697
DepMap; ACH-002301
Biological sample resources BioSample; SAMN03471256
Chemistry resources GDSC; 909697
PharmacoDB; RF48_1309_2019
Encyclopedic resources Wikidata; Q54949801
Gene expression databases ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-3610
GEO; GSM1670375
Polymorphism and mutation databases Cosmic; 909697
IARC_TP53; 21286
Proteomic databases PRIDE; PXD030304
Sequence databases EGA; EGAS00001000978
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number30