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Cellosaurus RF-48 (CVCL_1657)

[Text version]
Cell line name RF-48
Synonyms RF48
Accession CVCL_1657
Resource Identification Initiative To cite this cell line use: RF-48 (RRID:CVCL_1657)
Comments Problematic cell line: Misclassified. From a B-cell lymphoma and not from the ascites of a gastric adenocarcinoma (PubMed=12226758).
Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: COSMIC cell lines project.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Genomics; DNA methylation analysis.
Omics: Genomics; Whole exome sequencing.
Omics: Phenotyping; Drug screening.
Omics: Proteomics; Quantitative.
Omics: Transcriptomics; Microarray.
Omics: Variations; SNP array analysis.
Genome ancestry Source: PubMed=30894373

Origin% genome
African5.29
Native American31.68
East Asian, North3.25
East Asian, South0
South Asian2.87
European, North27.68
European, South29.24
Disease Lymphoma (NCIt: C3208)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_3580 ! RF-1
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-1863; Cosmic-CLP=909697

Markers:
AmelogeninX,Y
CSF1PO11
D5S81811,12
D7S82010,12
D13S31712
D16S53911,13
TH017,8
TPOX8,12
vWA15,16

Run an STR similarity search on this cell line
Publications

PubMed=7750094; DOI=10.1016/0304-3835(95)03717-b
Anastasios Nikolaos Salesiotis, Chung-Kuei Wang, Cheng-Dian Wang, Angelika Maria Burger, Hua Li, Arun Seth;
Identification of novel genes from stomach cancer cell lines by differential display.
Cancer Lett. 91:47-54(1995)

PubMed=12226758; DOI=10.1038/sj.onc.1205829
Jia-Fu Ji, Xin Chen, Suet Yi Leung, Jen-Tsan Ashley Chi, Kent Man Chu, Siu Tsan Yuen, Rui Li, Annie S.Y. Chan, Ji-You Li, Nina Dunphy, Samuel So;
Comprehensive analysis of the gene expression profiles in human gastric cancer cell lines.
Oncogene 21:6549-6556(2002)

PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113
Graham Robert Bignell, Christopher D. Greenman, Helen R. Davies, Adam P. Butler, Sarah Edkins, Jenny M. Andrews, Gemma Buck, Lina Chen, David Beare, Calli Latimer, Sara Widaa ...Show all 22 authors... , Jonathan Hinton, Ciara Fahey, Bei-Yuan Fu, Sajani Swamy, Gillian L. Dalgliesh, Bin Tean Teh, Panos Deloukas, Feng-Tang Yang, Peter J. Campbell, P. Andrew Futreal, Michael Rudolf Stratton; Show fewer authors
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469
Francesco Iorio, Theo A. Knijnenburg, Daniel J. Vis, Graham Robert Bignell, Michael Patrick Menden, Michael Schubert, Nanne Aben, Emanuel Goncalves, Syd Barthorpe, Howard Lightfoot, Thomas Cokelaer ...Show all 39 authors... , Patricia Greninger, Ewald van Dyk, Han Chang, Heshani de Silva, Holger Heyn, Xian-Ming Deng, Regina K. Egan, Qing-Song Liu, Tatiana Mironenko, Xeni Mitropoulos, Laura Richardson, Jin-Hua Wang, Ting-Hu Zhang, Sebastian Moran, Sergi Sayols, Maryam Soleimani, David Tamborero, Nuria Lopez-Bigas, Petra Ross-Macdonald, Manel Esteller, Nathanael S. Gray, Daniel Arie Haber, Michael Rudolf Stratton, Cyril Henri Benes, Lodewyk F.A. Wessels, Julio Saez-Rodriguez, Ultan McDermott, Mathew J. Garnett; Show fewer authors
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675
Julie Dutil, Zhi-Hua Chen, Alvaro N.A. Monteiro, Jamie K. Teer, Steven A. Eschrich;
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775
Emanuel Goncalves, Rebecca C. Poulos, Zhao-Xiang Cai, Syd Barthorpe, Srikanth S. Manda, Natasha Lucas, Alexandra Beck, Daniel Bucio-Noble, Michael Dausmann, Caitlin Hall, Michael Hecker ...Show all 32 authors... , Jennifer Koh, Howard Lightfoot, Sadia Mahboob, Iman Mali, James Morris, Laura Richardson, Akila J. Seneviratne, Rebecca Shepherd, Erin Sykes, Frances Thomas, Sara Valentini, Steven G. Williams, Yang-Xiu Wu, Dylan Xavier, Karen L. MacKenzie, Peter G. Hains, Brett Tully, Phillip James Robinson, Qing Zhong, Mathew J. Garnett, Roger Robert Reddel; Show fewer authors
Pan-cancer proteomic map of 949 human cell lines.
Cancer Cell 40:835-849.e8(2022)

Cross-references
Cell line collections (Providers) ATCC; CRL-1863 - Discontinued
IZSLER; BS TCL 208
Cell line databases/resources CLO; CLO_0037147
cancercelllines; CVCL_1657
Cell_Model_Passport; SIDM01092
Cosmic-CLP; 909697
DepMap; ACH-002301
LINCS_LDP; LCL-1896
Biological sample resources BioSample; SAMN03471256
Chemistry resources GDSC; 909697
PharmacoDB; RF48_1309_2019
Encyclopedic resources Wikidata; Q54949801
Gene expression databases ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-3610
GEO; GSM1670375
Polymorphism and mutation databases Cosmic; 909697
IARC_TP53; 21286
Proteomic databases PRIDE; PXD030304
Sequence databases EGA; EGAS00001000978
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number31