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Cellosaurus OC 315 (CVCL_1617)

[Text version]
Cell line name OC 315
Synonyms OC-315; OC315
Accession CVCL_1617
Resource Identification Initiative To cite this cell line use: OC 315 (RRID:CVCL_1617)
Comments Problematic cell line: Possibly contaminated. May be identical to OC 314 (Cellosaurus=CVCL_1616) according to STR profiling done at ICLC and to MSI data (PubMed=15677628).
Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Microsatellite instability: Instable (MSI-high) (PubMed=15677628).
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Disease Ovarian serous adenocarcinoma (NCIt: C7550)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 49Y
Category Cancer cell line
Publications

PubMed=8690298; DOI=10.1006/gyno.1996.0194
Angela Alama, Federica Barbieri, Anna Favre, Monica Cagnoli, Elvira Noviello, Franco Pedulla, Maurizio Viale, Gianni Foglia, Nicola Ragni;
Establishment and characterization of three new cell lines derived from the ascites of human ovarian carcinomas.
Gynecol. Oncol. 62:82-88(1996)

PubMed=15677628; DOI=10.1093/carcin/bgi032
Kylie Louise Gorringe, Suet-Feung Chin, Paul D.P. Pharoah, Joanne M. Staines, Carla Oliveira, Paul A.W. Edwards, Carlos Caldas;
Evidence that both genetic instability and selection contribute to the accumulation of chromosome alterations in cancer.
Carcinogenesis 26:923-930(2005)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103
Mahmoud Ghandi, Franklin W. Huang, Judit Jane-Valbuena, Gregory V. Kryukov, Christopher C. Lo, E. Robert McDonald 3rd, Jordi Ginesta Barretina, Ellen T. Gelfand, Craig M. Bielski, Hao-Xin Li, Kevin Hu ...Show all 68 authors... , Alexander Y. Andreev-Drakhlin, Jaegil Kim, Julian M. Hess, Brian J. Haas, Francois Aguet, Barbara A. Weir, Michael V. Rothberg, Brenton R. Paolella, Michael Scott Lawrence, Rehan Akbani, Yi-Ling Lu, Hong L. Tiv, Prafulla C. Gokhale, Antoine de Weck, Ali Amin Mansour, Coyin Oh, Juliann Shih, Kevin Hadi, Yanay Rosen, Jonathan Bistline, Kavitha Venkatesan, Anupama Reddy, Dmitriy Sonkin, Manway Liu, Joseph Lehar, Joshua M. Korn, Dale A. Porter, Michael D. Jones, Javad Golji, Giordano Caponigro, Jordan E. Taylor, Caitlin M. Dunning, Amanda L. Creech, Allison C. Warren, James M. McFarland, Mahdi Zamanighomi, Audrey Kauffmann, Nicolas Stransky, Marcin Imielinski, Yosef E. Maruvka, Andrew D. Cherniack, Aviad Tsherniak, Francisca Vazquez, Jacob D. Jaffe, Andrew Alan Lane, David M. Weinstock, Cory M. Johannessen, Michael P. Morrissey, Frank Stegmeier, Robert Schlegel, William Chun Hahn, Gad Getz, Gordon B. Mills, Jesse S. Boehm, Todd Robert Golub, Levi Alexander Garraway, William Raj Sellers; Show fewer authors
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections (Providers) ICLC; HTL98013 - Discontinued
Cell line databases/resources CLO; CLO_0008232
cancercelllines; CVCL_1617
Cell_Model_Passport; SIDM01823
DepMap; ACH-001144
Anatomy/cell type resources BTO; BTO_0006436
Chemistry resources PharmacoDB; OC315_1180_2019
Encyclopedic resources Wikidata; Q54931702
Gene expression databases GEO; GSM459737
Polymorphism and mutation databases Progenetix; CVCL_1617
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number21