Cellosaurus NCI-H630 (CVCL_1572)
| Cell line name | NCI-H630 | ||||||||||||||||||||
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| Synonyms | H630; H-630; NCIH630 | ||||||||||||||||||||
| Accession | CVCL_1572 | ||||||||||||||||||||
| Resource Identification Initiative | To cite this cell line use: NCI-H630 (RRID:CVCL_1572) | ||||||||||||||||||||
| Comments | Problematic cell line: Contaminated. The contaminant is not known. Seems to be a mixture of cell lines. Originally said to originate from a 60 year old male patient with a rectal carcinoma. Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). Part of: COSMIC cell lines project. Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00417. Population: Caucasian. Microsatellite instability: Instable (MSI-high) (PubMed=25926053; PubMed=31068700; Sanger). Omics: Genomics; DNA methylation analysis. Omics: Genomics; Whole exome sequencing. Omics: Phenotyping; Drug screening. Omics: Proteomics; PTM; Phosphorylation; Quantitative. Omics: Proteomics; Quantitative. Omics: Transcriptomics; Microarray. Omics: Variations; SNP array analysis. | ||||||||||||||||||||
| Sequence variations |
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| Genome ancestry | Source: PubMed=30894373
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| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||||
| Sex of cell | Sex unspecified | ||||||||||||||||||||
| Age at sampling | Age unspecified | ||||||||||||||||||||
| Category | Undefined cell line type | ||||||||||||||||||||
| STR profile | Source(s): ATCC=CRL-5833; Cosmic-CLP=908482; PubMed=25926053 Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||||
| Web pages | Info; ATCC; -; https://www.atcc.org/en/support/technical-support/faqs/nci-h630-atcc-crl-5833 Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx | ||||||||||||||||||||
| Publications | PubMed=3479249 PubMed=8806092; DOI=10.1002/jcb.240630505 PubMed=8806095; DOI=10.1002/jcb.240630508 PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113 PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662 PubMed=25926053; DOI=10.1038/ncomms8002 PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469 PubMed=28854368; DOI=10.1016/j.celrep.2017.08.010; PMCID=PMC5583477 PubMed=29444439; DOI=10.1016/j.celrep.2018.01.051; PMCID=PMC6343826 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675 PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103 | ||||||||||||||||||||
| Cross-references | |||||||||||||||||||||
| Cell line collections (Providers) | ATCC; CRL-5833 - Discontinued
IZSLER; BS TCL 191 KCLB; 90630 - Discontinued | ||||||||||||||||||||
| Cell line databases/resources | CLO; CLO_0008099
Cosmic-CLP; 908482 DepMap; ACH-002287 IGRhCellID; NCIH630 LINCS_LDP; LCL-1287 | ||||||||||||||||||||
| Biological sample resources | BioSample; SAMN03151846
BioSample; SAMN03481113 | ||||||||||||||||||||
| Chemistry resources | ChEMBL-Cells; CHEMBL3307966
ChEMBL-Targets; CHEMBL612540 GDSC; 908482 PharmacoDB; NCIH630_1122_2019 PubChem_Cell_line; CVCL_1572 | ||||||||||||||||||||
| Encyclopedic resources | Wikidata; Q54908089 | ||||||||||||||||||||
| Experimental variables resources | EFO; EFO_0002297 | ||||||||||||||||||||
| Gene expression databases | ArrayExpress; E-MTAB-38
ArrayExpress; E-MTAB-783 ArrayExpress; E-MTAB-3610 GEO; GSM452725 GEO; GSM452756 GEO; GSM453572 GEO; GSM454623 GEO; GSM454643 GEO; GSM454644 GEO; GSM454645 GEO; GSM1448143 GEO; GSM1670252 | ||||||||||||||||||||
| Polymorphism and mutation databases | Cosmic; 687535
Cosmic; 908482 Cosmic; 1187327 IARC_TP53; 21576 | ||||||||||||||||||||
| Proteomic databases | PRIDE; PXD005235 | ||||||||||||||||||||
| Sequence databases | EGA; EGAS00001000978 | ||||||||||||||||||||
| Entry history | |||||||||||||||||||||
| Entry creation | 04-Apr-2012 | ||||||||||||||||||||
| Last entry update | 10-Apr-2025 | ||||||||||||||||||||
| Version number | 39 | ||||||||||||||||||||