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Cellosaurus NCI-H498 (CVCL_1563)

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Cell line name NCI-H498
Synonyms H498; H-498
Accession CVCL_1563
Resource Identification Initiative To cite this cell line use: NCI-H498 (RRID:CVCL_1563)
Comments Population: Caucasian.
Microsatellite instability: Stable (MSS) (PubMed=25926053).
Omics: Transcriptomics; Microarray.
Derived from site: Metastatic; Peritoneum; UBERON=UBERON_0002358.
Disease Cecum adenocarcinoma (NCIt: C5543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
STR profile Source(s): ATCC=CCL-254; KCLB=10254; PubMed=25926053

Markers:
AmelogeninX
CSF1PO12
D2S133819,23
D3S135815
D5S81813
D7S8208,11
D8S117911,13
D13S3179,11
D16S5399,11
D18S5115
D19S43312,15
D21S1129,31
FGA22,24
Penta D9,10
Penta E5,15
TH017
TPOX8
vWA15

Run an STR similarity search on this cell line
Publications

PubMed=3479249
Jae-Gahb Park, Herbert Kazuto Oie, Paul Hendrick Sugarbaker, Jerry G. Henslee, Tchaw-Ren Chen, Bruce E. Johnson, Adi F. Gazdar;
Characteristics of cell lines established from human colorectal carcinoma.
Cancer Res. 47:6710-6718(1987)

PubMed=8806089; DOI=10.1002/jcb.240630502
Adi F. Gazdar, John D. Minna;
NCI series of cell lines: an historical perspective.
J. Cell. Biochem. Suppl. 24:1-11(1996)

PubMed=8806092; DOI=10.1002/jcb.240630505
Ruby M. Phelps, Bruce E. Johnson, Daniel Carlyle Ihde, Adi F. Gazdar, David P. Carbone, Patrick R. McClintock, Ritva Ilona Linnoila, Mary J. Matthews, Paul A. Bunn Jr., Desmond Niall Carney, John D. Minna, James L. Mulshine;
NCI-Navy Medical Oncology Branch cell line data base.
J. Cell. Biochem. Suppl. 24:32-91(1996)

PubMed=8806095; DOI=10.1002/jcb.240630508
Jae-Gahb Park, Adi F. Gazdar;
Biology of colorectal and gastric cancer cell lines.
J. Cell. Biochem. Suppl. 24:131-141(1996)

PubMed=25926053; DOI=10.1038/ncomms8002
Enzo Medico, Mariangela Russo, Gabriele Picco, Carlotta Cancelliere, Emanuele Valtorta, Giorgio Corti, Michela Buscarino, Claudio Isella, Simona Lamba, Barbara Martinoglio, Silvio Veronese ...Show all 19 authors... , Salvatore Siena, Andrea Sartore-Bianchi, Marco Beccuti, Marcella Mottolese, Michael Linnebacher, Francesca Cordero, Federica Di Nicolantonio, Alberto Bardelli; Show fewer authors
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
Nat. Commun. 6:7002.1-7002.10(2015)

Cross-references
Cell line collections (Providers) ATCC; CCL-254
KCLB; 10254
Cell line databases/resources CLO; CLO_0008090
cancercelllines; CVCL_1563
Biological sample resources BioSample; SAMN03471385
Encyclopedic resources Wikidata; Q54908069
Gene expression databases GEO; GSM513915
GEO; GSM514302
GEO; GSM1448214
Polymorphism and mutation databases Progenetix; CVCL_1563
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number24