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Cellosaurus NCI-H220 (CVCL_1541)

[Text version]
Cell line name NCI-H220
Synonyms H220; H-220
Accession CVCL_1541
Resource Identification Initiative To cite this cell line use: NCI-H220 (RRID:CVCL_1541)
Comments Population: African American.
Misspelling: NCI-N220; PubMed=6272398.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Disease Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 51Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-5825

Markers:
AmelogeninX,Y
CSF1PO10
D2S133816,24
D3S135817
D5S81811
D7S82010,11
D8S117915
D13S31712
D16S53910
D18S5116,18
D19S43313.2,14
D21S1128
FGA20
Penta D10
Penta E9,13
TH017,9.3
TPOX8,11
vWA16,18

Run an STR similarity search on this cell line
Publications

PubMed=6272398; DOI=10.1126/science.6272398
Moody T.W., Pert C.B., Gazdar A.F., Carney D.N., Minna J.D.
High levels of intracellular bombesin characterize human small-cell lung carcinoma.
Science 214:1246-1248(1981)

PubMed=2985257
Carney D.N., Gazdar A.F., Bepler G., Guccion J.G., Marangos P.J., Moody T.W., Zweig M.H., Minna J.D.
Establishment and identification of small cell lung cancer cell lines having classic and variant features.
Cancer Res. 45:2913-2923(1985)

PubMed=2986243; DOI=10.1007/978-3-642-82372-5_4
Whang-Peng J., Lee E.C.
Cytogenetics of human small cell lung cancer.
Recent Results Cancer Res. 97:37-46(1985)

PubMed=8806092; DOI=10.1002/jcb.240630505
Phelps R.M., Johnson B.E., Ihde D.C., Gazdar A.F., Carbone D.P., McClintock P.R., Linnoila R.I., Matthews M.J., Bunn P.A. Jr., Carney D.N., Minna J.D., Mulshine J.L.
NCI-Navy Medical Oncology Branch cell line data base.
J. Cell. Biochem. 63 Suppl. 24:32-91(1996)

PubMed=8806103; DOI=10.1002/jcb.240630516
Johnson B.E., Russell E., Simmons A.M., Phelps R.M., Steinberg S.M., Ihde D.C., Gazdar A.F.
MYC family DNA amplification in 126 tumor cell lines from patients with small cell lung cancer.
J. Cell. Biochem. 63 Suppl. 24:210-217(1996)

PubMed=31803961; DOI=10.1002/jcb.29564
Mulshine J.L., Ujhazy P., Antman M., Burgess C.M., Kuzmin I.A., Bunn P.A. Jr., Johnson B.E., Roth J.A., Pass H.I., Ross S.M., Aldige C.R., Wistuba I.I., Minna J.D.
From clinical specimens to human cancer preclinical models -- a journey the NCI-cell line database-25 years later.
J. Cell. Biochem. 121:3986-3999(2020)

Cross-references
Cell line collections (Providers) ATCC; CRL-5825
Cell line databases/resources CLO; CLO_0008065
LINCS_LDP; LCL-1852
Biological sample resources BioSample; SAMN03471745
Chemistry resources GDSC; 1330974
PharmacoDB; NCIH220_1079_2019
Encyclopedic resources Wikidata; Q54907942
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number26