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Cellosaurus NBsusSR (CVCL_1450)

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Cell line name NBsusSR
Synonyms NBSUSSR
Accession CVCL_1450
Resource Identification Initiative To cite this cell line use: NBsusSR (RRID:CVCL_1450)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: COSMIC cell lines project.
Population: Japanese.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Genomics; DNA methylation analysis.
Omics: Genomics; Whole exome sequencing.
Omics: Phenotyping; Drug screening.
Omics: Transcriptomics; Microarray.
Omics: Variations; SNP array analysis.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg213Ter (c.637C>T); ClinVar=VCV000043590; Zygosity=Homozygous (Cosmic-CLP=925342; DepMap=ACH-002340).
Genome ancestry Source: PubMed=30894373

Origin% genome
African1.34
Native American0
East Asian, North75.7
East Asian, South20.79
South Asian0.62
European, North0.87
European, South0.68
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 18Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP=925342; RCB=RCB0803

Markers:
AmelogeninX,Y
CSF1PO12,13
D5S81810,12
D7S82010,12
D13S3178,10
D16S53910,12
TH019
TPOX8,11
vWA15,18

Run an STR similarity search on this cell line
Publications

PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113
Graham Robert Bignell, Christopher D. Greenman, Helen R. Davies, Adam P. Butler, Sarah Edkins, Jenny M. Andrews, Gemma Buck, Lina Chen, David Beare, Calli Latimer, Sara Widaa ...Show all 22 authors... , Jonathan Hinton, Ciara Fahey, Bei-Yuan Fu, Sajani Swamy, Gillian L. Dalgliesh, Bin Tean Teh, Panos Deloukas, Feng-Tang Yang, Peter J. Campbell, P. Andrew Futreal, Michael Rudolf Stratton; Show fewer authors
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675
Julie Dutil, Zhi-Hua Chen, Alvaro N.A. Monteiro, Jamie K. Teer, Steven A. Eschrich;
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line collections (Providers) RCB; RCB0803
Cell line databases/resources CLO; CLO_0050117
cancercelllines; CVCL_1450
Cell_Model_Passport; SIDM00002
Cosmic-CLP; 925342
DepMap; ACH-002340
LINCS_LDP; LCL-1998
Biological sample resources BioSample; SAMN03472240
Chemistry resources ChEMBL-Cells; CHEMBL3308847
ChEMBL-Targets; CHEMBL2366150
GDSC; 925342
PharmacoDB; NBsusSR_995_2019
PubChem_Cell_line; CVCL_1450
Encyclopedic resources Wikidata; Q54907560
Gene expression databases ArrayExpress; E-MTAB-783
FANTOM5_SSTAR; 10607-108F4
GEO; GSM1670156
Polymorphism and mutation databases Cosmic; 925342
IARC_TP53; 27185
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number36