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Cellosaurus MC-1010 (CVCL_1396)

[Text version]
Cell line name MC-1010
Synonyms MC1010
Accession CVCL_1396
Resource Identification Initiative To cite this cell line use: MC-1010 (RRID:CVCL_1396)
Comments Group: Patented cell line.
Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: COSMIC cell lines project.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-12253.
Population: Caucasian.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Genome ancestry Source: PubMed=30894373

Origin% genome
African0.31
Native American0.93
East Asian, North2.01
East Asian, South0
South Asian0
European, North60.99
European, South35.76
Disease Adult acute myeloid leukemia (NCIt: C9154)
Acute myeloid leukemia (ORDO: Orphanet_519)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): Cosmic-CLP

Markers:
AmelogeninX,Y
CSF1PO11
D5S81811,14
D7S8208,12
D13S31711,12
D16S5399,13
TH016,9.3
TPOX8,11
vWA18

Run an STR similarity search on this cell line
Publications

PubMed=167748; DOI=10.1016/0006-291X(75)90355-1
Chang S.C.-S., Bernofsky C.
Correlation between DNA synthesis and intracellular NAD in cultured human leukemic lymphocytes.
Biochem. Biophys. Res. Commun. 64:539-545(1975)

PubMed=8594420; DOI=10.1007/BF00928153
Bernofsky C., Bandara B.M.R.
Spin trapping endogenous radicals in MC-1010 cells: evidence for hydroxyl radical and carbon-centered ascorbyl radical adducts.
Mol. Cell. Biochem. 148:155-164(1995)

Patent=US5804443
Bernofsky C.
Human monocytic leukemia cell line.
Patent number US5804443, 08-Sep-1998

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line collections (Providers) ATCC; CRL-12253
Cell line databases/resources cancercelllines; CVCL_1396
Cell_Model_Passport; SIDM00009
Cosmic-CLP; 907798
DepMap; ACH-002390
Chemistry resources GDSC; 907798
PharmacoDB; MC1010_884_2019
Encyclopedic resources Wikidata; Q54904166
Gene expression databases ArrayExpress; E-MTAB-783
Polymorphism and mutation databases Cosmic; 683546
Cosmic; 907798
IARC_TP53; 21486
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number21