Cellosaurus logo
expasy logo

Cellosaurus MC-1010 (CVCL_1396)

[Text][XML][JSON]
Cell line name MC-1010
Synonyms MC1010
Accession CVCL_1396
Resource Identification Initiative To cite this cell line use: MC-1010 (RRID:CVCL_1396)
Comments Group: Patented cell line.
Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: COSMIC cell lines project.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-12253.
Population: Caucasian.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Genomics; Whole exome sequencing.
Omics: Phenotyping; Drug screening.
Omics: Transcriptomics; Microarray.
Omics: Variations; SNP array analysis.
Genome ancestry Source: PubMed=30894373

Origin% genome
African0.31
Native American0.93
East Asian, North2.01
East Asian, South0
South Asian0
European, North60.99
European, South35.76
Disease Adult acute myeloid leukemia (NCIt: C9154)
Acute myeloid leukemia (ORDO: Orphanet_519)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): Cosmic-CLP=907798

Markers:
AmelogeninX,Y
CSF1PO11
D5S81811,14
D7S8208,12
D13S31711,12
D16S5399,13
TH016,9.3
TPOX8,11
vWA18

Run an STR similarity search on this cell line
Publications

PubMed=167748; DOI=10.1016/0006-291X(75)90355-1
Steve C.-S. Chang, Carl Bernofsky;
Correlation between DNA synthesis and intracellular NAD in cultured human leukemic lymphocytes.
Biochem. Biophys. Res. Commun. 64:539-545(1975)

PubMed=8594420; DOI=10.1007/BF00928153
Carl Bernofsky, B.M. Ratnayake Bandara;
Spin trapping endogenous radicals in MC-1010 cells: evidence for hydroxyl radical and carbon-centered ascorbyl radical adducts.
Mol. Cell. Biochem. 148:155-164(1995)

Patent=US5804443
Carl Bernofsky;
Human monocytic leukemia cell line.
Patent number US5804443, 08-Sep-1998

PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113
Graham Robert Bignell, Christopher D. Greenman, Helen R. Davies, Adam P. Butler, Sarah Edkins, Jenny M. Andrews, Gemma Buck, Lina Chen, David Beare, Calli Latimer, Sara Widaa ...Show all 22 authors... , Jonathan Hinton, Ciara Fahey, Bei-Yuan Fu, Sajani Swamy, Gillian L. Dalgliesh, Bin Tean Teh, Panos Deloukas, Feng-Tang Yang, Peter J. Campbell, P. Andrew Futreal, Michael Rudolf Stratton; Show fewer authors
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675
Julie Dutil, Zhi-Hua Chen, Alvaro N.A. Monteiro, Jamie K. Teer, Steven A. Eschrich;
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line databases/resources cancercelllines; CVCL_1396
Cell_Model_Passport; SIDM00009
Cosmic-CLP; 907798
DepMap; ACH-002390
Chemistry resources GDSC; 907798
PharmacoDB; MC1010_884_2019
Encyclopedic resources Wikidata; Q54904166
Gene expression databases ArrayExpress; E-MTAB-783
Polymorphism and mutation databases Cosmic; 683546
Cosmic; 907798
IARC_TP53; 21486
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number23