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Cellosaurus GA-10 clone 20 (CVCL_1223)

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Cell line name GA-10 clone 20
Synonyms GA-10 (Clone 20); GA-10-Clone-20
Accession CVCL_1223
Resource Identification Initiative To cite this cell line use: GA-10 clone 20 (RRID:CVCL_1223)
Comments Population: Caucasian.
Virology: EBV-negative.
Omics: Transcriptomics; Microarray.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro152Leu (c.455C>T); ClinVar=VCV000142766; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ile232Asn (c.695T>A); ClinVar=VCV000850008; Zygosity=Heterozygous (from parent cell line).
Disease Adult Burkitt leukemia (NCIt: C7954)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1222 (GA-10)
Sex of cell Male
Age at sampling 41Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-2394

Markers:
AmelogeninX,Y
CSF1PO10
D2S133820
D3S135818
D5S81811
D7S8208,10
D8S117911,13
D13S31711
D16S53911,12
D18S5114,18
D19S43312,14
D21S1128,30
FGA20,23
Penta D9,13
Penta E5,12
TH019,9.3
TPOX8,11
vWA16,20

Run an STR similarity search on this cell line
Publications

PubMed=11482875; DOI=10.1006/bcmd.2001.0428
Aaron Paul Rapoport, Michelle Simons-Evelyn, Timothy Chen, Rochel Sidell, Shannon Luhowskyj, Karen Rosell, Tom Obrig, David Hicks, Patricia M. Hinkle, Moon H. Nahm, Richard A. Insel, Camille N. Abboud;
Flavopiridol induces apoptosis and caspase-3 activation of a newly characterized Burkitt's lymphoma cell line containing mutant p53 genes.
Blood Cells Mol. Dis. 27:610-624(2001)

PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113
Graham Robert Bignell, Christopher D. Greenman, Helen R. Davies, Adam P. Butler, Sarah Edkins, Jenny M. Andrews, Gemma Buck, Lina Chen, David Beare, Calli Latimer, Sara Widaa ...Show all 22 authors... , Jonathan Hinton, Ciara Fahey, Bei-Yuan Fu, Sajani Swamy, Gillian L. Dalgliesh, Bin Tean Teh, Panos Deloukas, Feng-Tang Yang, Peter J. Campbell, P. Andrew Futreal, Michael Rudolf Stratton; Show fewer authors
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

Cross-references
Cell line collections (Providers) ATCC; CRL-2394
Cell line databases/resources CLO; CLO_0003440
cancercelllines; CVCL_1223
Cell_Model_Passport; SIDM01255
LINCS_LDP; LCL-2035
Encyclopedic resources Wikidata; Q54835416
Gene expression databases ArrayExpress; E-MTAB-783
Polymorphism and mutation databases Cosmic; 906866
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number28