Cellosaurus cell line ECC4 [Human rectal adenocarcinoma] (CVCL

Cellosaurus ECC4 [Human rectal adenocarcinoma] (CVCL_1190)

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Cell line name

ECC4 [Human rectal adenocarcinoma]

Synonyms

ECC 4

Accession

CVCL_1190

Resource Identification Initiative

To cite this cell line use: ECC4 [Human rectal adenocarcinoma] (RRID:CVCL_1190)

Comments

Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Japanese.
Doubling time: 140 hours (PubMed=8392984).
Omics: Genomics; DNA methylation analysis.
Omics: Phenotyping; Drug screening.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Rectum; UBERON=UBERON_0001052.

Disease

Rectal adenocarcinoma (NCIt: C9383)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

45Y

Category

Cancer cell line

STR profile

Source(s): DepMap=ACH-002024; RCB=RCB0982

Markers:

Amelogenin	X
CSF1PO	12
D3S1358	15
D5S818	11
D7S820	10,12
D8S1179	9,10
D13S317	11
D16S539	10
D18S51	14
D21S11	30
FGA	20
Penta D	9
Penta E	10,12
TH01	7,9
TPOX	8,11
vWA	14

Publications

PubMed=8392984; DOI=10.1002/ijc.2910540617
Takato Fujiwara, Teiichi Motoyama, Noriko Ishihara, Hidenobu Watanabe, Toshiro Kumanishi, Kanefusa Kato, Hiroshi Ichinose, Toshiharu Nagatsu;
Characterization of four new cell lines derived from small-cell gastrointestinal carcinoma.
Int. J. Cancer 54:965-971(1993)

PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113
Graham Robert Bignell, Christopher D. Greenman, Helen R. Davies, Adam P. Butler, Sarah Edkins, Jenny M. Andrews, Gemma Buck, Lina Chen, David Beare, Calli Latimer, Sara Widaa ...Show all 22 authors... , Jonathan Hinton, Ciara Fahey, Bei-Yuan Fu, Sajani Swamy, Gillian L. Dalgliesh, Bin Tean Teh, Panos Deloukas, Feng-Tang Yang, Peter J. Campbell, P. Andrew Futreal, Michael Rudolf Stratton; Show fewer authors
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

Cross-references

Cell line collections (Providers)

RCB; RCB0982

Cell line databases/resources

CLO; CLO_0051398
cancercelllines; CVCL_1190
Cell_Model_Passport; SIDM00069
DepMap; ACH-002024
LINCS_LDP; LCL-1115

Biological sample resources

BioSample; SAMN03472195

Chemistry resources

ChEMBL-Cells; CHEMBL3308162
ChEMBL-Targets; CHEMBL2366367
GDSC; 906850
PharmacoDB; ECC4_319_2019
PubChem_Cell_line; CVCL_1190

Encyclopedic resources

Wikidata; Q54831925

Gene expression databases

ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-3610
FANTOM5_SSTAR; 10609-108F6
GEO; GSM1669752

Polymorphism and mutation databases

Cosmic; 906850
IARC_TP53; 21320

Sequence databases

EGA; EGAS00001000978

Entry history

Entry creation

04-Apr-2012

Last entry update

10-Apr-2025

Version number