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Cellosaurus DJM-1 (CVCL_1172)

[Text version]

Cell line name DJM-1
Synonyms DJM1
Accession CVCL_1172
Resource Identification Initiative To cite this cell line use: DJM-1 (RRID:CVCL_1172)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: COSMIC cell lines project.
Population: Japanese.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: Deep quantitative proteome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Skin.
Sequence variations
  • Mutation; HGNC; 6770; SMAD4; Simple; p.Ser144Ter (c.431C>G); Zygosity=Homozygous (Cosmic-CLP; DepMap).
  • Mutation; HGNC; 11998; TP53; Simple; p.Gly266Val (c.797G>T); ClinVar=VCV000233303; Zygosity=Heterozygous (Cosmic-CLP; DepMap).
Genome ancestry Source: PubMed=30894373

Origin% genome
African0
Native American0
East Asian, North79.62
East Asian, South19.44
South Asian0.93
European, North0
European, South0
Disease Skin squamous cell carcinoma (NCIt: C4819)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_8157 (BSCC-93)
Sex of cell Female
Age at sampling 87Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; RCB

Markers:
AmelogeninX
CSF1PO11,12
D5S81810,13
D7S8207,8
D13S3178
D16S53910
TH016
TPOX8,9
vWA14,17

Run an STR similarity search on this cell line
Publications

PubMed=2439611; DOI=10.1111/1523-1747.ep12470554
Kitajima Y., Inoue S., Yaoita H.
Effects of pemphigus antibody on the regeneration of cell-cell contact in keratinocyte cultures grown in low to normal Ca++ concentration.
J. Invest. Dermatol. 89:167-171(1987)

PubMed=1919059; DOI=10.1111/1523-1747.ep12491818
Katayama H., Kitagawa S., Masuyama J.-I., Yaoita H.
Polymorphonuclear leukocyte-induced detachment of cultured epidermal carcinoma cells from the substratum.
J. Invest. Dermatol. 97:949-952(1991)

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X.-M., Egan R.K., Liu Q.-S., Mironenko T., Mitropoulos X., Richardson L., Wang J.-H., Zhang T.-H., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010
Goncalves E., Poulos R.C., Cai Z.-X., Barthorpe S., Manda S.S., Lucas N., Beck A., Bucio-Noble D., Dausmann M., Hall C., Hecker M., Koh J., Lightfoot H., Mahboob S., Mali I., Morris J., Richardson L., Seneviratne A.J., Shepherd R., Sykes E., Thomas F., Valentini S., Williams S.G., Wu Y.-X., Xavier D., MacKenzie K.L., Hains P.G., Tully B., Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.
Pan-cancer proteomic map of 949 human cell lines.
Cancer Cell 40:835-849.e8(2022)

Cross-references
Cell line collections BCRJ; 0375
RCB; RCB0736
Cell line databases/resources CLO; CLO_0050680
Cell_Model_Passport; SIDM00281
Cosmic-CLP; 906841
DepMap; ACH-002100
LINCS_LDP; LCL-1405
Biological sample resources BioSample; SAMN03472223
Chemistry resources ChEMBL-Cells; CHEMBL3308190
ChEMBL-Targets; CHEMBL2366264
GDSC; 906841
PharmacoDB; DJM1_292_2019
PubChem_Cell_line; CVCL_1172
Encyclopedic resources Wikidata; Q54831104
Gene expression databases ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-3610
GEO; GSM1669733
Polymorphism and mutation databases Cosmic; 906841
IARC_TP53; 21302
Proteomic databases PRIDE; PXD030304
Sequence databases EGA; EGAS00001000978
Entry history
Entry creation04-Apr-2012
Last entry update15-Dec-2022
Version number30